The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 136: poly(U)-binding-splicing factor PUF60 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 Q8T6B9 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI)
(2 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
11 Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA)
(1 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
11 Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI) Q9UHX1 (/IPI)
(1 more)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
11 Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA) Q9UHX1 (/HDA)
(1 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q3UEB3 (/ISO) Q3UEB3 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q8T6B9 (/ISS)
Poly(U) RNA binding GO:0008266
Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule.
1 Q8T6B9 (/ISS)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
11 Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS)
(1 more)
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
1 Q8T6B9 (/IMP)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
1 Q8T6B9 (/HMP)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
1 Q8T6B9 (/IMP)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
1 Q8T6B9 (/IC)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
1 Q8T6B9 (/IMP)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
1 Q8T6B9 (/ISS)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 Q8T6B9 (/IMP)
MRNA splice site selection GO:0006376
Selection of a splice site by components of the assembling spliceosome.
1 Q8T6B9 (/IMP)
Cystoblast division GO:0007282
Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.
1 Q8T6B9 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q8T6B9 (/IMP)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 Q8T6B9 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
15 E9PMU7 (/IDA) E9PN18 (/IDA) E9PQ56 (/IDA) H0YEM1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA)
(5 more)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
13 E9PQ56 (/IDA) H0YEM1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA) Q9UHX1 (/IDA)
(3 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
11 Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS) Q9UHX1 (/TAS)
(1 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q3UEB3 (/ISO) Q3UEB3 (/ISO)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
2 Q3UEB3 (/ISO) Q3UEB3 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8T6B9 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8T6B9 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q8T6B9 (/IPI)
Precatalytic spliceosome GO:0071011
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
1 Q8T6B9 (/HDA)
Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
1 Q8T6B9 (/HDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...