The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Erythroid Transcription Factor GATA-1, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 137: GR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
1 O42551 (/IDA)
Glucocorticoid receptor activity GO:0004883
Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
1 O42541 (/IDA)
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
1 O42551 (/IDA)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 O42541 (/IDA)
Regulation of metabolic process GO:0019222
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
1 O42541 (/IMP)
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
1 O42551 (/IMP)
Multicellular organismal response to stress GO:0033555
Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
1 O42541 (/IEP)
Light adaption GO:0036367
The ability of a photoreceptor to adjust to varying levels of light.
1 O42541 (/IMP)
Luteinizing hormone signaling pathway GO:0042700
The series of molecular signals mediated by luteinizing hormone.
1 O42551 (/IMP)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
1 O42541 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 O42541 (/IDA)
Circadian behavior GO:0048512
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
1 O42541 (/IGI)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
1 O42541 (/IMP)
Ion homeostasis GO:0050801
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
1 O42541 (/IMP)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
1 O42541 (/IMP)
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
1 O42541 (/IDA)
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
1 O42541 (/IMP)
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
1 O42541 (/IMP)
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
1 O42541 (/IMP)
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
1 O42541 (/IMP)
Response to dexamethasone GO:0071548
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
1 O42541 (/IDA)
Proton export across plasma membrane GO:0120029
The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.
1 O42541 (/IMP)
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
1 O42541 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O42541 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O42541 (/IDA)
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