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CATH Superfamily 3.30.479.10

6-pyruvoyl tetrahydropterin synthase/QueD

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
6-pyruvoyl tetrahydropterin synthase/QueD
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: 6-pyruvoyl tetrahydrobiopterin synthase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
6-pyruvoyltetrahydropterin synthase. [EC: 4.2.3.12]
7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8- tetrahydropterin + triphosphate.
  • Catalyzes triphosphate elimination and an intramolecular redox reaction.
  • The product is 6-pyruvoyltetrahydrobiopterin.
  • Involved in the de novo synthesis of tetrahydrobiopterin from GTP, with the other enzymes involved being EC 1.1.1.153 and EC 3.5.4.16.
  • Formerly EC 4.6.1.10.
 18 A0A0J9R4V5 A0A0J9R4V5 A0A0J9R4V5 A0A2J8X1X3 A0A2J8X1X3 B4I631 B4I631 B4I631 O02058 P27213
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