The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
6-pyruvoyl tetrahydropterin synthase/QueD
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 6-carboxy-5,6,7,8-tetrahydropterin synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
74 P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA)
(64 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
74 P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA)
(64 more)
6-carboxy-5,6,7,8-tetrahydropterin synthase activity GO:0070497
Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.
74 P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA) P65870 (/IDA)
(64 more)
6-pyruvoyltetrahydropterin synthase activity GO:0003874
Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate.
9 Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Queuosine biosynthetic process GO:0008616
The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
74 P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP) P65870 (/IMP)
(64 more)
Tetrahydrobiopterin biosynthetic process GO:0006729
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
9 Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS) Q9KSF7 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.