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CATH Superfamily 3.30.429.10

Macrophage Migration Inhibitory Factor

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Macrophage Migration Inhibitory Factor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Macrophage migration inhibitory factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)
Host cell surface receptor binding GO:0046789
Interacting selectively and non-covalently with a receptor on the host cell surface.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Evasion or tolerance of host immune response GO:0020012
Any process, either active or passive, by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)
Maurer's cleft GO:0020036
A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)
Host cell cytoplasm GO:0030430
The cytoplasm of a host cell.
 13 Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA) Q8I5C5 (/IDA)
(3 more)