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CATH Superfamily 3.30.428.10

HIT-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HIT-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: m7GpppX diphosphatase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. [EC: 3.6.1.59]
A 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] + H(2)O = N(7)- methylguanosine 5'-phosphate + a 5'-diphospho-[mRNA].
  • The enzyme removes (decaps) the N(7)-methylguanosine 5-phosphate cap from an mRNA degraded to a maximal length of 10 nucleotides.
  • Decapping is an important process in the control of eukaryotic mRNA degradation.
  • The enzyme functions to clear the cell of cap structure following decay of the RNA body.
  • The nematode enzyme can also decap triply methylated substrates, 5'-(N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-[mRNA].
  • Formerly EC 3.6.1.30.
 13 A0A384MTI8 A0A384MTI8 A0A480PF49 A0A480PF49 D3K0N9 G5EFS4 Q8K4F7 Q8MIZ3 Q8MIZ3 Q8MJJ7
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