The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 911: Chromatin accessibility complex (CHRAC)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
5 Q5BI37 (/TAS) Q95RV8 (/TAS) Q9NG24 (/TAS) Q9V9T4 (/TAS) Q9Y0W1 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q5BI37 (/IPI) Q95RV8 (/IPI) Q9NG24 (/IPI) Q9V9T4 (/IPI) Q9Y0W1 (/IPI)
Nucleosome-dependent ATPase activity GO:0070615
Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of one or more nucleosomes.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin assembly or disassembly GO:0006333
The formation or destruction of chromatin structures.
5 Q5BI37 (/TAS) Q95RV8 (/TAS) Q9NG24 (/TAS) Q9V9T4 (/TAS) Q9Y0W1 (/TAS)
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
5 Q5BI37 (/IMP) Q95RV8 (/IMP) Q9NG24 (/IMP) Q9V9T4 (/IMP) Q9Y0W1 (/IMP)
Nucleosome positioning GO:0016584
Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
Regulation of heterochromatin assembly GO:0031445
Any process that modulates the frequency, rate, extent or location of heterochromatin formation.
5 Q5BI37 (/IMP) Q95RV8 (/IMP) Q9NG24 (/IMP) Q9V9T4 (/IMP) Q9Y0W1 (/IMP)
Chromatin assembly GO:0031497
The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
Nucleosome mobilization GO:0042766
The movement of nucleosomes along a DNA fragment.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
Nucleosome mobilization GO:0042766
The movement of nucleosomes along a DNA fragment.
5 Q5BI37 (/TAS) Q95RV8 (/TAS) Q9NG24 (/TAS) Q9V9T4 (/TAS) Q9Y0W1 (/TAS)
Regulation of ATPase activity GO:0043462
Any process that modulates the rate of ATP hydrolysis by an ATPase.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
5 Q5BI37 (/IMP) Q95RV8 (/IMP) Q9NG24 (/IMP) Q9V9T4 (/IMP) Q9Y0W1 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
CHRAC GO:0008623
An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
ACF complex GO:0016590
An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.
5 Q5BI37 (/IDA) Q95RV8 (/IDA) Q9NG24 (/IDA) Q9V9T4 (/IDA) Q9Y0W1 (/IDA)
ACF complex GO:0016590
An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.
5 Q5BI37 (/IPI) Q95RV8 (/IPI) Q9NG24 (/IPI) Q9V9T4 (/IPI) Q9Y0W1 (/IPI)
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