The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 843: E3 ubiquitin-protein ligase PEP5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P12868 (/IPI) P12868 (/IPI) P12868 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Golgi to endosome transport GO:0006895
The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
|
3 | P12868 (/IGI) P12868 (/IGI) P12868 (/IGI) |
|
Histone ubiquitination GO:0016574
The modification of histones by addition of ubiquitin groups.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
|
Regulation of vacuole fusion, non-autophagic GO:0032889
Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
|
Regulation of SNARE complex assembly GO:0035542
Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
|
Histone catabolic process GO:0036205
The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
|
3 | P12868 (/IMP) P12868 (/IMP) P12868 (/IMP) |
|
Vacuole fusion, non-autophagic GO:0042144
The fusion of two vacuole membranes to form a single vacuole.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
|
Vacuole fusion, non-autophagic GO:0042144
The fusion of two vacuole membranes to form a single vacuole.
|
3 | P12868 (/IMP) P12868 (/IMP) P12868 (/IMP) |
|
Late endosome to vacuole transport GO:0045324
The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
|
3 | P12868 (/IGI) P12868 (/IGI) P12868 (/IGI) |
|
Vesicle tethering GO:0099022
The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
|
HOPS complex GO:0030897
A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.
|
3 | P12868 (/IPI) P12868 (/IPI) P12868 (/IPI) |
|
CORVET complex GO:0033263
A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.
|
3 | P12868 (/IDA) P12868 (/IDA) P12868 (/IDA) |
