The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

Generation of cells within the nervous system.

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.

The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.

Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.

The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.

The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.

The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).

The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).

Any process that stops, prevents or reduces the rate or extent of cell proliferation.

Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.

The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.

The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.

The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.

The release of a mature ovum/oocyte from an ovary.

Any process that activates or increases the activity of a transporter.

Any process that activates or increases the activity of a transporter.

Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.

Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.

The modification of a histone by addition of one or more methyl groups to a lysine residue.

The stages of blood cell formation that take place within the embryo.

The stages of blood cell formation that take place within the embryo.

The specific behavior of an organism in response to a novel environment or stimulus.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.

The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.

The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.

The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.

The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.

A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.

The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.

Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.

Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.

Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.

The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.

A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.

The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.

The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.

Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.

Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.

The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.

The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.

Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation.

Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.

Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.

Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.

Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.

Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.

Any process that activates or increases the frequency, rate or extent of cellular response to drug.

Any process that activates or increases the frequency, rate or extent of cellular response to drug.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

That part of the nuclear content other than the chromosomes or the nucleolus.

A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.

A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

That part of the nuclear content other than the chromosomes or the nucleolus.

That part of the nuclear content other than the chromosomes or the nucleolus.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.

A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.

A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.

A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.