The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 661: Rco1p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-like protein ligase activity GO:0061659
Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.
1 Q09698 (/ISM)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
4 Q04779 (/IGI) Q04779 (/IGI) Q04779 (/IGI) Q04779 (/IGI)
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
4 Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
4 Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP)
Negative regulation of antisense RNA transcription GO:0060195
Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
4 Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP)
Transfer RNA gene-mediated silencing GO:0061587
The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.
4 Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP) Q04779 (/IMP)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q09698 (/IC)
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
1 Q09698 (/ISO)
Protein modification by small protein conjugation or removal GO:0070647
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
1 Q09698 (/IC)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q04779 (/HDA) Q04779 (/HDA) Q04779 (/HDA) Q04779 (/HDA) Q09698 (/HDA)
Rpd3S complex GO:0032221
A eukaryotically conserved histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).
5 Q04779 (/IDA) Q04779 (/IDA) Q04779 (/IDA) Q04779 (/IDA) Q09698 (/IDA)
Histone deacetylase complex GO:0000118
A protein complex that possesses histone deacetylase activity.
4 Q04779 (/IDA) Q04779 (/IDA) Q04779 (/IDA) Q04779 (/IDA)
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
1 Q09698 (/HDA)
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