The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 426: DMA1p Ubiquitin-protein ligase (E3)
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
8 | P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P53924 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
8 | P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P53924 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q10322 (/IPI) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q10322 (/ISM) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
1 | Q10322 (/IDA) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
|
8 | P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P53924 (/IGI) |
|
Septin ring assembly GO:0000921
The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
|
8 | P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P53924 (/IGI) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
8 | P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P53924 (/IGI) |
|
Mitotic spindle orientation checkpoint GO:0031578
A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.
|
8 | P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P53924 (/IGI) |
|
Cellular bud neck septin ring organization GO:0032186
Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.
|
8 | P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P53924 (/IGI) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
8 | P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P53924 (/IDA) |
|
Regulation of formin-nucleated actin cable assembly GO:0090337
Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
|
8 | P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P38823 (/IMP) P53924 (/IMP) |
|
Regulation of formin-nucleated actin cable assembly GO:0090337
Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
|
8 | P38823 (/IPI) P38823 (/IPI) P38823 (/IPI) P38823 (/IPI) P38823 (/IPI) P38823 (/IPI) P38823 (/IPI) P53924 (/IPI) |
|
Protein localization to bud neck GO:0097271
A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.
|
8 | P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P38823 (/IGI) P53924 (/IGI) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
7 | P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) P38823 (/IDA) |
|
Mitotic spindle assembly checkpoint GO:0007094
A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
|
1 | Q10322 (/IMP) |
|
Negative regulation of septation initiation signaling GO:0031030
Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.
|
1 | Q10322 (/IMP) |
|
Negative regulation of septation initiation signaling GO:0031030
Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.
|
1 | Q10322 (/IPI) |
|
Protein modification by small protein conjugation or removal GO:0070647
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
|
1 | Q10322 (/IC) |
|
Negative regulation of protein localization to spindle pole body GO:1902364
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.
|
1 | Q10322 (/IMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P38823 (/HDA) P38823 (/HDA) P38823 (/HDA) P38823 (/HDA) P38823 (/HDA) P38823 (/HDA) P38823 (/HDA) P53924 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10322 (/IC) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q10322 (/HDA) |
|
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
|
1 | P53924 (/IMP) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | Q10322 (/HDA) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | Q10322 (/IDA) |
|
Cellular bud neck split septin rings GO:0032177
Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.
|
1 | P53924 (/IMP) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | Q10322 (/HDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | Q10322 (/IDA) |
|
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
|
1 | Q10322 (/IDA) |
|
Medial cortical node GO:0071341
A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.
|
1 | Q10322 (/IDA) |
