The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 378: TRAF-type zinc finger domain-containing 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | D3ZPQ3 (/IPI) O14545 (/IPI) O14545 (/IPI) Q80V31 (/IPI) |
|
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
|
2 | Q385V1 (/ISM) Q385V1 (/ISM) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | Q385V1 (/ISM) Q385V1 (/ISM) |
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | Q4QGE1 (/IMP) |
|
Glycine binding GO:0016594
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
|
1 | D3Z8X7 (/IMP) |
|
Glycine binding GO:0016594
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
|
1 | Q80V31 (/ISO) |
|
Glutamate binding GO:0016595
Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.
|
1 | D3Z8X7 (/IMP) |
|
Glutamate binding GO:0016595
Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.
|
1 | Q80V31 (/ISO) |
|
Thienylcyclohexylpiperidine binding GO:0016596
Interacting selectively and non-covalently with thienylcyclohexylpiperidine.
|
1 | D3Z8X7 (/IMP) |
|
Thienylcyclohexylpiperidine binding GO:0016596
Interacting selectively and non-covalently with thienylcyclohexylpiperidine.
|
1 | Q80V31 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of innate immune response GO:0045824
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
|
3 | O14545 (/ISS) O14545 (/ISS) Q4R970 (/ISS) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
3 | Q385V1 (/IMP) Q385V1 (/IMP) Q4QGE1 (/IMP) |
|
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
|
1 | D3ZPQ3 (/IDA) |
|
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
|
1 | Q5NBU8 (/ISO) |
|
Response to interferon-beta GO:0035456
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
|
1 | Q5NBU8 (/ISO) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
1 | Q4QGE1 (/ISO) |
|
Axonemal microtubule depolymerization GO:0060404
The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.
|
1 | Q4QGE1 (/IMP) |
|
Cilium disassembly GO:0061523
A cellular process that results in the breakdown of a cilium.
|
1 | Q4QGE1 (/IMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
|
3 | Q385V1 (/IDA) Q385V1 (/IDA) Q4QGE1 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q385V1 (/IDA) Q385V1 (/IDA) |
|
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
|
2 | Q385V1 (/ISM) Q385V1 (/ISM) |
|
Ciliary tip GO:0097542
Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
|
2 | Q385V1 (/IDA) Q385V1 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | D3ZPQ3 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q5NBU8 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q4QGE1 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q5NBU8 (/ISO) |
|
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
|
1 | Q80V31 (/ISO) |
|
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
|
1 | Q80V31 (/ISS) |
|
Ciliary tip GO:0097542
Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
|
1 | Q4QGE1 (/ISO) |
