The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 343: E3 SUMO-protein ligase NSE2 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q96MF7 (/IPI) Q96MF7 (/IPI) Q96MF7 (/IPI) Q96MF7 (/IPI)
SUMO transferase activity GO:0019789
Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.
4 Q96MF7 (/EXP) Q96MF7 (/EXP) Q96MF7 (/EXP) Q96MF7 (/EXP)
SUMO transferase activity GO:0019789
Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.
4 Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA)
SUMO transferase activity GO:0019789
Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
SUMO transferase activity GO:0019789
Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.
1 Q91VT1 (/ISO)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Telomere maintenance via recombination GO:0000722
Any recombinational process that contributes to the maintenance of proper telomeric length.
4 Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP)
Telomere maintenance via recombination GO:0000722
Any recombinational process that contributes to the maintenance of proper telomeric length.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
4 Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP)
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Positive regulation of maintenance of mitotic sister chromatid cohesion GO:0034184
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
4 Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP)
Positive regulation of maintenance of mitotic sister chromatid cohesion GO:0034184
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Positive regulation of mitotic metaphase/anaphase transition GO:0045842
Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
4 Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP)
Positive regulation of mitotic metaphase/anaphase transition GO:0045842
Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Cellular senescence GO:0090398
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
4 Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP) Q96MF7 (/IMP)
Cellular senescence GO:0090398
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Telomere maintenance via recombination GO:0000722
Any recombinational process that contributes to the maintenance of proper telomeric length.
1 Q91VT1 (/ISO)
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
1 Q91VT1 (/ISO)
Positive regulation of maintenance of mitotic sister chromatid cohesion GO:0034184
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
1 Q91VT1 (/ISO)
Positive regulation of mitotic metaphase/anaphase transition GO:0045842
Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
1 Q91VT1 (/ISO)
Cellular senescence GO:0090398
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
1 Q91VT1 (/ISO)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 A0A024R9J6 (/IDA) A0A024R9J6 (/IDA) A0A024R9J6 (/IDA) A0A024R9J6 (/IDA) E5RFJ1 (/IDA) E5RFJ1 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
10 A0A024R9J6 (/IDA) A0A024R9J6 (/IDA) A0A024R9J6 (/IDA) A0A024R9J6 (/IDA) E5RFJ1 (/IDA) E5RFJ1 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
4 Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 Q96MF7 (/TAS) Q96MF7 (/TAS) Q96MF7 (/TAS) Q96MF7 (/TAS)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
4 Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Smc5-Smc6 complex GO:0030915
A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
4 Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA) Q96MF7 (/IDA)
Smc5-Smc6 complex GO:0030915
A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
4 Q32KY9 (/ISS) Q4V8A0 (/ISS) Q7ZXH2 (/ISS) Q91VT1 (/ISS)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
1 Q91VT1 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q91VT1 (/ISO)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q91VT1 (/ISO)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
1 Q91VT1 (/ISO)
Smc5-Smc6 complex GO:0030915
A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
1 Q91VT1 (/ISO)
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