The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 305: RING finger protein 112
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | O70418 (/NAS) Q9ULX5 (/NAS) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q96DY5 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q96DY5 (/IPI) |
|
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
1 | Q96DY5 (/IMP) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q96DY5 (/IDA) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
1 | Q96DY5 (/IDA) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q96DY5 (/ISS) |
|
Response to hydroperoxide GO:0033194
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Cell death in response to oxidative stress GO:0036473
Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Cell death in response to hydrogen peroxide GO:0036474
Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2).
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Embryonic brain development GO:1990403
The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
2 | O70418 (/ISS) Q08DF2 (/ISS) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | Q9ULX5 (/IDA) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | Q96DY5 (/ISO) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | Q9ULX5 (/IDA) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | Q96DY5 (/IMP) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | Q96DY5 (/ISO) |
|
Response to hydroperoxide GO:0033194
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
|
1 | Q96DY5 (/IDA) |
|
Cell death in response to oxidative stress GO:0036473
Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.
|
1 | Q96DY5 (/IMP) |
|
Cell death in response to hydrogen peroxide GO:0036474
Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2).
|
1 | Q96DY5 (/IMP) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q96DY5 (/IMP) |
|
Positive regulation of glial cell differentiation GO:0045687
Any process that activates or increases the frequency, rate or extent of glia cell differentiation.
|
1 | Q96DY5 (/IMP) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
1 | Q96DY5 (/IDA) |
|
Positive regulation of cell cycle arrest GO:0071158
Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
|
1 | Q96DY5 (/IMP) |
|
Embryonic brain development GO:1990403
The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.
|
1 | Q96DY5 (/IMP) |
There are 18 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
|
3 | O70418 (/ISS) Q08DF2 (/ISS) Q9ULX5 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q96DY5 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q96DY5 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q96DY5 (/IDA) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | Q96DY5 (/IDA) |
|
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
|
1 | Q96DY5 (/IDA) |
|
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | Q96DY5 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q96DY5 (/IDA) |
|
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
1 | Q96DY5 (/IDA) |
|
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
|
1 | Q96DY5 (/IDA) |
