The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 262: E3 ubiquitin-protein ligase MARCH5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
171 M9PDP1 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS)
(161 more)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
53 Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP)
(43 more)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
53 Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI)
(43 more)
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
53 Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI) Q9NX47 (/IPI)
(43 more)
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
6 M9PDP1 (/ISM) Q8T8V4 (/ISM) Q961R6 (/ISM) Q9VB61 (/ISM) Q9VN18 (/ISM) Q9W4S2 (/ISM)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
165 Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS)
(155 more)
Regulation of mitochondrial fission GO:0090140
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
165 Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS)
(155 more)
Negative regulation of cell aging GO:0090344
Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
165 Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS)
(155 more)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Protein localization to mitochondrion GO:0070585
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
53 Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP)
(43 more)
Protein localization to mitochondrion GO:0070585
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Regulation of mitochondrial fission GO:0090140
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
53 Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP)
(43 more)
Regulation of mitochondrial fission GO:0090140
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Positive regulation of mitochondrial fission GO:0090141
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
53 Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP)
(43 more)
Positive regulation of mitochondrial fission GO:0090141
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Negative regulation of cell aging GO:0090344
Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
53 Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP) Q9NX47 (/IMP)
(43 more)
Negative regulation of cell aging GO:0090344
Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
6 M9PDP1 (/ISS) Q8T8V4 (/ISS) Q961R6 (/ISS) Q9VB61 (/ISS) Q9VN18 (/ISS) Q9W4S2 (/ISS)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
171 M9PDP1 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS)
(161 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
165 Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS) Q0X0A5 (/ISS)
(155 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
53 Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA) Q9NX47 (/IDA)
(43 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
53 Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO) Q3KNM2 (/ISO)
(43 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
53 Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA) Q9NX47 (/HDA)
(43 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
6 M9PDP1 (/ISS) Q8T8V4 (/ISS) Q961R6 (/ISS) Q9VB61 (/ISS) Q9VN18 (/ISS) Q9W4S2 (/ISS)
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