The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 246: E3 ubiquitin-protein ligase TRIM33 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q99PP7 (/IPI) Q9UPN9 (/IPI) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | Q9UPN9 (/TAS) |
|
Nuclear receptor binding GO:0016922
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
|
1 | F1P4C7 (/ISS) |
|
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
|
1 | Q9UPN9 (/IPI) |
|
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
|
1 | Q99PP7 (/ISO) |
|
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
|
1 | Q99PP7 (/ISS) |
|
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
|
1 | Q9UPN9 (/IPI) |
|
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
|
1 | Q99PP7 (/ISO) |
|
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
|
1 | Q99PP7 (/ISS) |
There are 23 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q9UPN9 (/TAS) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q9UPN9 (/IDA) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q99PP7 (/ISO) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q99PP7 (/ISS) |
|
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
1 | Q9UPN9 (/IDA) |
|
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
1 | Q99PP7 (/ISO) |
|
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
1 | Q99PP7 (/ISS) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | Q6E2N3 (/IGI) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | Q6E2N3 (/IMP) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q9UPN9 (/IDA) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q99PP7 (/ISO) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q99PP7 (/ISS) |
|
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | Q6E2N3 (/IMP) |
|
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
|
1 | Q6E2N3 (/IMP) |
|
Regulation of transcription elongation from RNA polymerase II promoter GO:0034243
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | Q6E2N3 (/IGI) |
|
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
1 | Q6E2N3 (/IMP) |
|
Post-embryonic hemopoiesis GO:0035166
The stages of blood cell formation that take place after completion of embryonic development.
|
1 | Q6E2N3 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9UPN9 (/NAS) |
|
Developmental pigmentation GO:0048066
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
|
1 | Q6E2N3 (/IMP) |
|
Macrophage chemotaxis GO:0048246
The movement of a macrophage in response to an external stimulus.
|
1 | Q6E2N3 (/IMP) |
|
Primitive hemopoiesis GO:0060215
A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
|
1 | Q6E2N3 (/IMP) |
|
Macrophage migration GO:1905517
The orderly movement of a macrophage from one site to another.
|
1 | Q6E2N3 (/IMP) |
|
Neutrophil migration GO:1990266
The movement of a neutrophil within or between different tissues and organs of the body.
|
1 | Q6E2N3 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q99PP7 (/IDA) Q9UPN9 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q99PP7 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9UPN9 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | F1P4C7 (/ISS) |
