The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 219: PHD finger protein 6 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 20 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
28 |
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
(18 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
28 |
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
Q8IWS0 (/HDA)
(18 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
28 |
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
(18 more) |
|
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
28 |
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
Q8IWS0 (/IPI)
(18 more) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q9D4J7 (/ISO) |
|
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
1 | Q9D4J7 (/ISO) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q9D4J7 (/ISO) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q9D4J7 (/ISO) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | Q9D4J7 (/ISO) |
|
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
|
1 | Q9D4J7 (/ISO) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q9D4J7 (/ISO) |
|
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
|
1 | Q9D4J7 (/ISO) |
|
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
1 | Q9D4J7 (/ISO) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
28 |
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
(18 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q9D4J7 (/ISO) |
|
Blastocyst hatching GO:0001835
The hatching of the cellular blastocyst from the zona pellucida.
|
1 | Q9D4J7 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
50 |
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
(40 more) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
49 |
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
A0A0D9SGE8 (/IDA)
(39 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
28 |
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
Q8IWS0 (/IDA)
(18 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9D4J7 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9D4J7 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9D4J7 (/ISO) |
