The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 181: RING-type E3 ubiquitin transferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
3 Q0IMG9 (/IDA) Q0IMG9 (/IDA) Q9SNC6 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q0IMG9 (/IPI) Q0IMG9 (/IPI) Q9SNC6 (/IPI)
Transmembrane receptor protein serine/threonine kinase binding GO:0070696
Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.
1 Q9SNC6 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
3 Q0IMG9 (/IDA) Q0IMG9 (/IDA) Q9SNC6 (/IDA)
Negative regulation of defense response GO:0031348
Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
2 Q0IMG9 (/IMP) Q0IMG9 (/IMP)
Negative regulation of programmed cell death GO:0043069
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
2 Q0IMG9 (/IMP) Q0IMG9 (/IMP)
Regulation of long-day photoperiodism, flowering GO:0048586
Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
2 Q0IMG9 (/IMP) Q0IMG9 (/IMP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
1 Q9SNC6 (/IGI)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q9SNC6 (/IMP)
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
1 Q9SNC6 (/IGI)
Regulation of photoperiodism, flowering GO:2000028
Any process that modulates the frequency, rate or extent of photoperiodism, flowering.
1 Q9SNC6 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q0IMG9 (/IDA) Q0IMG9 (/IDA) Q9SNC6 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q0IMG9 (/IDA) Q0IMG9 (/IDA) Q9SNC6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9SNC6 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...