The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1394: CRE-MADD-2 protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 B1GRL4 (/IPI) Q9UAQ3 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 B1GRL4 (/IPI) Q9UAQ3 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 B1GRL4 (/IPI) Q9UAQ3 (/IPI)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q9UAQ3 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
2 B1GRL4 (/IMP) Q9UAQ3 (/IMP)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
2 B1GRL4 (/IMP) Q9UAQ3 (/IMP)
Dorsal/ventral axon guidance GO:0033563
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
2 B1GRL4 (/IMP) Q9UAQ3 (/IMP)
Axon midline choice point recognition GO:0016199
The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
1 Q9UAQ3 (/IGI)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q9UAQ3 (/IDA)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
1 Q9UAQ3 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
2 B1GRL4 (/IDA) Q9UAQ3 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
2 B1GRL4 (/IDA) Q9UAQ3 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 B1GRL4 (/IDA) Q9UAQ3 (/IDA)
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
2 B1GRL4 (/IDA) Q9UAQ3 (/IDA)
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