The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 1156: Degringolade, isoform A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polymerase II repressing transcription factor binding GO:0001103
Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription.
|
3 | A0A0B4LHT4 (/IPI) Q8I0J6 (/IPI) Q9VNJ0 (/IPI) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | A0A0B4LHT4 (/ISM) Q8I0J6 (/ISM) Q9VNJ0 (/ISM) |
|
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
|
3 | A0A0B4LHT4 (/IPI) Q8I0J6 (/IPI) Q9VNJ0 (/IPI) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9VNJ0 (/IPI) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
|
3 | A0A0B4LHT4 (/IMP) Q8I0J6 (/IMP) Q9VNJ0 (/IMP) |
|
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
|
3 | A0A0B4LHT4 (/IMP) Q8I0J6 (/IMP) Q9VNJ0 (/IMP) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
Neurogenesis GO:0022008
Generation of cells within the nervous system.
|
3 | A0A0B4LHT4 (/IGI) Q8I0J6 (/IGI) Q9VNJ0 (/IGI) |
|
Regulation of protein binding GO:0043393
Any process that modulates the frequency, rate or extent of protein binding.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
Regulation of embryonic development GO:0045995
Any process that modulates the frequency, rate or extent of embryonic development.
|
3 | A0A0B4LHT4 (/IMP) Q8I0J6 (/IMP) Q9VNJ0 (/IMP) |
|
Regulation of establishment of protein localization GO:0070201
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
Positive regulation of antimicrobial peptide production GO:0002225
Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.
|
1 | Q9VNJ0 (/IMP) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | Q9VNJ0 (/IMP) |
|
Positive regulation of Toll signaling pathway GO:0045752
Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.
|
1 | Q9VNJ0 (/IGI) |
|
Positive regulation of peptidoglycan recognition protein signaling pathway GO:0061059
Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
|
1 | Q9VNJ0 (/IGI) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
|
SUMO-targeted ubiquitin ligase complex GO:0033768
A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.
|
3 | A0A0B4LHT4 (/IC) Q8I0J6 (/IC) Q9VNJ0 (/IC) |
|
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
|
3 | A0A0B4LHT4 (/IDA) Q8I0J6 (/IDA) Q9VNJ0 (/IDA) |
