The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 109: Zinc finger FYVE domain-containing protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
1-phosphatidylinositol binding GO:0005545
Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
6 | Q6GLQ0 (/ISS) Q6GLQ0 (/ISS) Q6ZPM1 (/ISS) Q6ZPM1 (/ISS) Q810J8 (/ISS) Q810J8 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9HBF4 (/IPI) Q9HBF4 (/IPI) |
1-phosphatidylinositol binding GO:0005545
Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
1-phosphatidylinositol binding GO:0005545
Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | Q9HBF4 (/NAS) Q9HBF4 (/NAS) |
Phosphatidylinositol-3,4-bisphosphate binding GO:0043325
Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Phosphatidylinositol-3,4-bisphosphate binding GO:0043325
Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of phosphatase activity GO:0010923
Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
4 | Q5RFL4 (/ISS) Q5RFL4 (/ISS) Q810J8 (/ISS) Q810J8 (/ISS) |
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Negative regulation of phosphatase activity GO:0010923
Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Negative regulation of phosphatase activity GO:0010923
Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
6 | Q6GLQ0 (/ISS) Q6GLQ0 (/ISS) Q6ZPM1 (/ISS) Q6ZPM1 (/ISS) Q810J8 (/ISS) Q810J8 (/ISS) |
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
|
6 | Q6GLQ0 (/ISS) Q6GLQ0 (/ISS) Q6ZPM1 (/ISS) Q6ZPM1 (/ISS) Q810J8 (/ISS) Q810J8 (/ISS) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
6 | Q6GLQ0 (/ISS) Q6GLQ0 (/ISS) Q6ZPM1 (/ISS) Q6ZPM1 (/ISS) Q810J8 (/ISS) Q810J8 (/ISS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | G3V5N8 (/IDA) G3V5N8 (/IDA) Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Phagophore assembly site GO:0000407
Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Phagophore assembly site GO:0000407
Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Mitochondria-associated endoplasmic reticulum membrane GO:0044233
A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Mitochondria-associated endoplasmic reticulum membrane GO:0044233
A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Extrinsic component of omegasome membrane GO:0097629
The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Extrinsic component of omegasome membrane GO:0097629
The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |
Omegasome GO:1990462
Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.
|
2 | Q9HBF4 (/IDA) Q9HBF4 (/IDA) |
Omegasome GO:1990462
Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.
|
2 | Q810J8 (/ISO) Q810J8 (/ISO) |