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CATH Superfamily 3.30.360.20

RNA 3'-terminal phosphate cyclase, insert domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
RNA 3'-terminal phosphate cyclase, insert domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: RNA 3'-terminal phosphate cyclase, insert domain

Structural domains comprising this superfamily share the structure of the insert domain in RNA 3'-terminal phosphate cyclase. RNA 3'-terminal phosphate cyclase is a type of RNA cyclase which catalyses the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. It is comprised of two domains and its smaller insert domain disrupts the large domain.

These enzymes might be responsible for production of the cyclic phosphate RNA ends that are known to be required by many RNA ligases in both prokaryotes and eukaryotes PMID:10673421. The role of this insert domain remains unknown

GO Diversity

Unique GO annotations
22 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
2820 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 24
Domain clusters (>95% seq id): 4
Domain clusters (>35% seq id): 3
Unique PDBs: 11
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 27
Function
Unique EC: 2
Unique GO: 22
Taxonomy
Unique Species: 2820