The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 5: S-adenosylmethionine synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
157 P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA)
(147 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
157 P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS)
(147 more)
Methionine adenosyltransferase activity GO:0004478
Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.
157 P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA)
(147 more)
Methionine adenosyltransferase activity GO:0004478
Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.
157 P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS)
(147 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
157 P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI)
(147 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
157 P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS)
(147 more)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
157 P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA)
(147 more)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
157 P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP)
(147 more)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
157 P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS) P0A819 (/NAS)
(147 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
157 P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI) P0A817 (/IPI)
(147 more)
Methionine adenosyltransferase activity GO:0004478
Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.
4 Q9KUP3 (/ISS) Q9KUP3 (/ISS) Q9KUP3 (/ISS) Q9KUP3 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
157 P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP)
(147 more)
S-adenosylmethionine cycle GO:0033353
A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.
157 P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP) P0A817 (/IMP)
(147 more)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
4 Q9KUP3 (/ISS) Q9KUP3 (/ISS) Q9KUP3 (/ISS) Q9KUP3 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
157 P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA) P0A817 (/HDA)
(147 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
157 P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA) P0A817 (/IDA)
(147 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...