The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Hect, E3 ligase catalytic domain
".
FunFam 13: E3 ubiquitin-protein ligase TRIP12 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
10 | A0A0B4JCV6 (/ISS) A0A0B4JCW5 (/ISS) A0A0B4JD62 (/ISS) A0A0B4JDA1 (/ISS) A0A0B4JDB5 (/ISS) A0A0B4LGQ5 (/ISS) A0A0B4LGR2 (/ISS) A0A0B4LHQ4 (/ISS) F1RCR6 (/ISS) Q9VN58 (/ISS) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
10 | A0A0B4JCV6 (/ISS) A0A0B4JCW5 (/ISS) A0A0B4JD62 (/ISS) A0A0B4JDA1 (/ISS) A0A0B4JDB5 (/ISS) A0A0B4LGQ5 (/ISS) A0A0B4LGR2 (/ISS) A0A0B4LHQ4 (/ISS) F1RCR6 (/ISS) Q9VN58 (/ISS) |
Positive regulation of circadian rhythm GO:0042753
Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
|
9 | A0A0B4JCV6 (/IMP) A0A0B4JCW5 (/IMP) A0A0B4JD62 (/IMP) A0A0B4JDA1 (/IMP) A0A0B4JDB5 (/IMP) A0A0B4LGQ5 (/IMP) A0A0B4LGR2 (/IMP) A0A0B4LHQ4 (/IMP) Q9VN58 (/IMP) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
9 | A0A0B4JCV6 (/IMP) A0A0B4JCW5 (/IMP) A0A0B4JD62 (/IMP) A0A0B4JDA1 (/IMP) A0A0B4JDB5 (/IMP) A0A0B4LGQ5 (/IMP) A0A0B4LGR2 (/IMP) A0A0B4LHQ4 (/IMP) Q9VN58 (/IMP) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | F1RCR6 (/ISS) |
Regulation of embryonic development GO:0045995
Any process that modulates the frequency, rate or extent of embryonic development.
|
1 | F1RCR6 (/ISS) |
Negative regulation of histone H2A K63-linked ubiquitination GO:1901315
Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.
|
1 | F1RCR6 (/ISS) |
Negative regulation of double-strand break repair GO:2000780
Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.
|
1 | F1RCR6 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | A0A0B4JCV6 (/ISS) A0A0B4JCW5 (/ISS) A0A0B4JD62 (/ISS) A0A0B4JDA1 (/ISS) A0A0B4JDB5 (/ISS) A0A0B4LGQ5 (/ISS) A0A0B4LGR2 (/ISS) A0A0B4LHQ4 (/ISS) Q9VN58 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q382A4 (/IDA) Q382A4 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | F1RCR6 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q4Q5H3 (/ISO) |