The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cyclin-dependent kinase, regulatory subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cyclin-dependent kinases regulatory subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
97 P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI) P33552 (/IPI)
(87 more)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
22 P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA) P56390 (/IDA)
(12 more)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
2 A8XMF2 (/ISS) A8XMF2 (/ISS)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 Q17868 (/IPI)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
74 P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI)
(64 more)
Mitotic cell cycle phase transition GO:0044772
The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
74 P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI)
(64 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
52 P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI) P61025 (/IGI)
(42 more)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
22 P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI) P56390 (/IGI)
(12 more)
Meiosis I GO:0007127
The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
22 P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP) P56390 (/IMP)
(12 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
6 Q24152 (/ISS) Q24152 (/ISS) Q24152 (/ISS) Q24152 (/ISS) Q24152 (/ISS) Q24152 (/ISS)
Spindle assembly involved in female meiosis I GO:0007057
The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Female meiotic nuclear division GO:0007143
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Female meiosis I GO:0007144
The cell cycle process in which the first meiotic division occurs in the female germline.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Histoblast morphogenesis GO:0007488
The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Syncytial blastoderm mitotic cell cycle GO:0035186
Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
6 Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP) Q24152 (/IMP)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
3 Q9VHN1 (/IMP) Q9VHN1 (/IMP) Q9VHN1 (/IMP)
Endomitotic cell cycle GO:0007113
A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
3 Q9VHN1 (/IMP) Q9VHN1 (/IMP) Q9VHN1 (/IMP)
Regulation of mitotic cell cycle, embryonic GO:0009794
Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.
2 A8XMF2 (/ISS) A8XMF2 (/ISS)
Regulation of mitotic cell cycle, embryonic GO:0009794
Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.
1 Q17868 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
52 P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS) P61024 (/TAS)
(42 more)
SCF ubiquitin ligase complex GO:0019005
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
3 Q9VHN1 (/IDA) Q9VHN1 (/IDA) Q9VHN1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q17868 (/IC)
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