The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"SIR2/SIRT2 'Small Domain'
".
FunFam 14: NAD-dependent histone deacetylase SIR2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 0 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
|
1 | O59923 (/IMP) |
|
Inheritance of oxidatively modified proteins involved in replicative cell aging GO:0001319
A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells.
|
1 | O59923 (/IMP) |
|
Regulation of cell differentiation GO:0045595
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
|
1 | O59923 (/IGI) |
|
Regulation of cell differentiation GO:0045595
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
|
1 | O59923 (/IMP) |
|
Negative regulation of DNA recombination at telomere GO:0048239
Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.
|
1 | O59923 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.