The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 914: Zinc finger protein 16

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P17020 (/ISA) P17020 (/ISA) P17020 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P17020 (/NAS) P17020 (/NAS) P17020 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P17020 (/IPI) P17020 (/IPI) P17020 (/IPI)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Positive regulation of kinase activity GO:0033674
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Positive regulation of megakaryocyte differentiation GO:0045654
Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Cellular response to sodium dodecyl sulfate GO:0072707
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Positive regulation of cell cycle phase transition GO:1901989
Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)
Positive regulation of kinase activity GO:0033674
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
3 P17020 (/IMP) P17020 (/IMP) P17020 (/IMP)
Positive regulation of megakaryocyte differentiation GO:0045654
Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.
3 P17020 (/IMP) P17020 (/IMP) P17020 (/IMP)
Cellular response to sodium dodecyl sulfate GO:0072707
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)
Positive regulation of cell cycle phase transition GO:1901989
Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A1YF12 (/ISS) A1YF12 (/ISS) A1YF12 (/ISS) A2T759 (/ISS) A2T759 (/ISS) A2T759 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
3 P17020 (/IDA) P17020 (/IDA) P17020 (/IDA)
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