The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Classic Zinc Finger
".
FunFam 82: Putative zinc finger E-box-binding homeobox 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 26 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
E-box binding GO:0070888
Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
|
5 | P36197 (/ISS) P37275 (/ISS) Q60542 (/ISS) Q60542 (/ISS) Q62947 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O60315 (/IPI) P37275 (/IPI) Q62947 (/IPI) Q64318 (/IPI) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | O60315 (/IDA) P37275 (/IDA) Q64318 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | O60315 (/ISA) P37275 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | O60315 (/ISM) P37275 (/ISM) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | O60315 (/NAS) P37275 (/NAS) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q64318 (/ISO) Q9R0G7 (/ISO) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | Q62947 (/IDA) Q64318 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | P37275 (/TAS) Q62947 (/TAS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | P37275 (/TAS) Q62947 (/TAS) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | O60315 (/IDA) Q62947 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | Q64318 (/ISO) Q9R0G7 (/ISO) |
|
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
1 | P28166 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P28166 (/IDA) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q9R0G7 (/IMP) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P28166 (/TAS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q64318 (/ISO) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
1 | Q62947 (/IDA) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
1 | Q64318 (/ISO) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | Q64318 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | P37275 (/TAS) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
1 | P37275 (/TAS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
1 | Q64318 (/IPI) |
|
Phosphatase regulator activity GO:0019208
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
|
1 | O60315 (/NAS) |
|
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
|
1 | Q9R0G7 (/IDA) |
|
E-box binding GO:0070888
Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
|
1 | Q64318 (/IDA) |
There are 97 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
11 |
A0A0R4IWE5 (/IMP)
A0A286Y942 (/IMP)
A0A2R8QDL5 (/IMP)
A0A2R8QLF5 (/IMP)
A0A2R8RT96 (/IMP)
B0LVE9 (/IMP)
B0LVF0 (/IMP)
B5DE38 (/IMP)
F1QY45 (/IMP)
F1R6J7 (/IMP)
(1 more) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
10 | A0A0R4IWE5 (/IGI) A0A286Y942 (/IGI) A0A2R8QDL5 (/IGI) A0A2R8QLF5 (/IGI) A0A2R8RT96 (/IGI) B0LVE9 (/IGI) B0LVF0 (/IGI) B5DE38 (/IGI) F1QY45 (/IGI) F1R6J7 (/IGI) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
10 | A0A0R4IWE5 (/IGI) A0A286Y942 (/IGI) A0A2R8QDL5 (/IGI) A0A2R8QLF5 (/IGI) A0A2R8RT96 (/IGI) B0LVE9 (/IGI) B0LVF0 (/IGI) B5DE38 (/IGI) F1QY45 (/IGI) F1R6J7 (/IGI) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
10 | A0A0R4IWE5 (/IMP) A0A286Y942 (/IMP) A0A2R8QDL5 (/IMP) A0A2R8QLF5 (/IMP) A0A2R8RT96 (/IMP) B0LVE9 (/IMP) B0LVF0 (/IMP) B5DE38 (/IMP) F1QY45 (/IMP) F1R6J7 (/IMP) |
|
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
10 | A0A0R4IWE5 (/IGI) A0A286Y942 (/IGI) A0A2R8QDL5 (/IGI) A0A2R8QLF5 (/IGI) A0A2R8RT96 (/IGI) B0LVE9 (/IGI) B0LVF0 (/IGI) B5DE38 (/IGI) F1QY45 (/IGI) F1R6J7 (/IGI) |
|
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
10 | A0A0R4IWE5 (/IMP) A0A286Y942 (/IMP) A0A2R8QDL5 (/IMP) A0A2R8QLF5 (/IMP) A0A2R8RT96 (/IMP) B0LVE9 (/IMP) B0LVF0 (/IMP) B5DE38 (/IMP) F1QY45 (/IMP) F1R6J7 (/IMP) |
|
Convergent extension involved in axis elongation GO:0060028
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
|
10 | A0A0R4IWE5 (/IGI) A0A286Y942 (/IGI) A0A2R8QDL5 (/IGI) A0A2R8QLF5 (/IGI) A0A2R8RT96 (/IGI) B0LVE9 (/IGI) B0LVF0 (/IGI) B5DE38 (/IGI) F1QY45 (/IGI) F1R6J7 (/IGI) |
|
Dorsal convergence GO:0060030
The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.
|
10 | A0A0R4IWE5 (/IGI) A0A286Y942 (/IGI) A0A2R8QDL5 (/IGI) A0A2R8QLF5 (/IGI) A0A2R8RT96 (/IGI) B0LVE9 (/IGI) B0LVF0 (/IGI) B5DE38 (/IGI) F1QY45 (/IGI) F1R6J7 (/IGI) |
|
Regulation of gastrulation GO:0010470
Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.
|
6 | A0A2R8QF92 (/IGI) A0A2R8QV74 (/IGI) F1QBD3 (/IGI) F1QMZ5 (/IGI) F1QPM7 (/IGI) Q9DEH7 (/IGI) |
|
Negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037
Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
|
6 | A0A286Y942 (/IMP) A0A2R8QLF5 (/IMP) A0A2R8RT96 (/IMP) B0LVE9 (/IMP) B5DE38 (/IMP) F1QY45 (/IMP) |
|
Dorsal convergence GO:0060030
The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.
|
6 | A0A286Y942 (/IMP) A0A2R8QLF5 (/IMP) A0A2R8RT96 (/IMP) B0LVE9 (/IMP) B5DE38 (/IMP) F1QY45 (/IMP) |
|
Regulation of cell-cell adhesion involved in gastrulation GO:0070587
Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.
|
6 | A0A2R8QF92 (/IGI) A0A2R8QV74 (/IGI) F1QBD3 (/IGI) F1QMZ5 (/IGI) F1QPM7 (/IGI) Q9DEH7 (/IGI) |
|
Fibroblast growth factor receptor signaling pathway involved in somitogenesis GO:0090243
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.
|
6 | A0A286Y942 (/IMP) A0A2R8QLF5 (/IMP) A0A2R8RT96 (/IMP) B0LVE9 (/IMP) B5DE38 (/IMP) F1QY45 (/IMP) |
|
Neural crest cell migration GO:0001755
The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
|
5 | A0A0R4IWE5 (/IMP) A0A2R8QDL5 (/IMP) B0LVF0 (/IMP) F1R6J7 (/IMP) Q9R0G7 (/IMP) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
5 | P36197 (/ISS) P37275 (/ISS) Q60542 (/ISS) Q60542 (/ISS) Q62947 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | P36197 (/ISS) Q60542 (/ISS) Q60542 (/ISS) Q62947 (/ISS) Q64318 (/ISS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
4 | O60315 (/IDA) P28166 (/IDA) P37275 (/IDA) Q62947 (/IDA) |
|
Intrahepatic bile duct development GO:0035622
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
|
4 | A0A0R4IWE5 (/IMP) A0A2R8QDL5 (/IMP) B0LVF0 (/IMP) F1R6J7 (/IMP) |
|
Convergent extension involved in axis elongation GO:0060028
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
|
4 | A0A0R4IWE5 (/IMP) A0A2R8QDL5 (/IMP) B0LVF0 (/IMP) F1R6J7 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | O60315 (/IMP) Q64318 (/IMP) Q9R0G7 (/IMP) |
|
Gastrulation GO:0007369
A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
3 | A0A2R8QF92 (/IMP) F1QPM7 (/IMP) Q9DEH7 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | O60315 (/IMP) Q62947 (/IMP) Q9R0G7 (/IMP) |
|
Smooth muscle tissue development GO:0048745
The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.
|
3 | A0A2R8QV74 (/IMP) F1QBD3 (/IMP) F1QMZ5 (/IMP) |
|
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
|
3 | A0A2R8QF92 (/IGI) F1QPM7 (/IGI) Q9DEH7 (/IGI) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q64318 (/ISO) Q9R0G7 (/ISO) |
|
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
2 | Q64318 (/IGI) Q9R0G7 (/IGI) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P37275 (/IDA) Q64318 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q64318 (/ISO) Q9R0G7 (/ISO) |
|
Positive regulation of melanin biosynthetic process GO:0048023
Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
|
2 | O60315 (/IC) Q9R0G7 (/IC) |
|
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
|
2 | Q64318 (/IGI) Q9R0G7 (/IGI) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | G5EBU4 (/ISS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | P37275 (/TAS) |
|
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
|
1 | Q9R0G7 (/IMP) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | P37275 (/TAS) |
|
Pole cell migration GO:0007280
The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form.
|
1 | P28166 (/TAS) |
|
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
|
1 | Q64318 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | P28166 (/IEP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | O60315 (/NAS) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | G5EBU4 (/IMP) |
|
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | P28166 (/IEP) |
|
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | P28166 (/IGI) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | P28166 (/NAS) |
|
Hemocyte development GO:0007516
The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
|
1 | P28166 (/IMP) |
|
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | P28166 (/IMP) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q64318 (/IMP) |
|
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
|
1 | P28166 (/IMP) |
|
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
|
1 | P28166 (/TAS) |
|
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
|
1 | P28166 (/TAS) |
|
Regulation of mesenchymal cell proliferation GO:0010464
Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
|
1 | Q64318 (/IMP) |
|
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
|
1 | Q62947 (/IEP) |
|
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
1 | Q64318 (/IGI) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P37275 (/TAS) |
|
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
|
1 | P28166 (/IMP) |
|
Corpus callosum morphogenesis GO:0021540
The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.
|
1 | Q9R0G7 (/IMP) |
|
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
|
1 | Q9R0G7 (/IMP) |
|
Cell proliferation in forebrain GO:0021846
The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.
|
1 | Q9R0G7 (/IMP) |
|
Corticospinal tract morphogenesis GO:0021957
Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.
|
1 | Q9R0G7 (/IMP) |
|
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
|
1 | Q9R0G7 (/IMP) |
|
Negative regulation of epithelial cell differentiation GO:0030857
Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.
|
1 | Q64318 (/IMP) |
|
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
|
1 | Q62947 (/IEP) |
|
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
1 | Q62947 (/IEP) |
|
Regulation of T cell differentiation in thymus GO:0033081
Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.
|
1 | Q64318 (/IMP) |
|
Positive regulation of JUN kinase activity GO:0043507
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
|
1 | Q9R0G7 (/IMP) |
|
Negative regulation of endothelial cell differentiation GO:0045602
Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
|
1 | P37275 (/IMP) |
|
Negative regulation of endothelial cell differentiation GO:0045602
Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
|
1 | Q64318 (/ISO) |
|
Positive regulation of melanocyte differentiation GO:0045636
Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.
|
1 | Q9R0G7 (/IMP) |
|
Positive regulation of melanocyte differentiation GO:0045636
Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.
|
1 | O60315 (/ISS) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q64318 (/IDA) |
|
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
|
1 | G5EBU4 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P37275 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q64318 (/ISO) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q64318 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q64318 (/IGI) |
|
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
1 | P28166 (/IMP) |
|
Developmental pigmentation GO:0048066
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
|
1 | Q9R0G7 (/IMP) |
|
Developmental pigmentation GO:0048066
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
|
1 | O60315 (/ISS) |
|
Somatic stem cell division GO:0048103
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
|
1 | P28166 (/IMP) |
|
Animal organ development GO:0048513
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | Q64318 (/IMP) |
|
Lymph gland development GO:0048542
The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
|
1 | P28166 (/IMP) |
|
Embryonic camera-type eye morphogenesis GO:0048596
The process in which the anatomical structures of the eye are generated and organized during embryonic development.
|
1 | Q64318 (/IMP) |
|
Collateral sprouting GO:0048668
The process in which outgrowths develop from the shafts of existing axons.
|
1 | Q9R0G7 (/IMP) |
|
Embryonic skeletal system morphogenesis GO:0048704
The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
|
1 | Q64318 (/IMP) |
|
Semicircular canal morphogenesis GO:0048752
The process in which the anatomical structures of the semicircular canals are generated and organized.
|
1 | Q64318 (/IMP) |
|
Positive regulation of axonogenesis GO:0050772
Any process that activates or increases the frequency, rate or extent of axonogenesis.
|
1 | Q9R0G7 (/IMP) |
|
Negative regulation of muscle cell differentiation GO:0051148
Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.
|
1 | P28166 (/IMP) |
|
Regulation of smooth muscle cell differentiation GO:0051150
Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.
|
1 | Q64318 (/IMP) |
|
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | Q64318 (/IMP) |
|
Garland nephrocyte differentiation GO:0061321
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
1 | P28166 (/IMP) |
|
Mammillary axonal complex development GO:0061373
The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.
|
1 | Q9R0G7 (/IMP) |
|
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
1 | Q64318 (/IDA) |
|
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
1 | Q62947 (/IEP) |
|
Cochlea morphogenesis GO:0090103
The process in which the cochlea is generated and organized.
|
1 | Q64318 (/IMP) |
|
Melanocyte migration GO:0097324
The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
|
1 | Q9R0G7 (/IMP) |
|
Melanocyte migration GO:0097324
The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
|
1 | O60315 (/ISS) |
|
Positive regulation of lens fiber cell differentiation GO:1902748
Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.
|
1 | Q9R0G7 (/IMP) |
|
Regulation of melanosome organization GO:1903056
Any process that modulates the frequency, rate or extent of melanosome organization.
|
1 | Q9R0G7 (/IMP) |
|
Regulation of melanosome organization GO:1903056
Any process that modulates the frequency, rate or extent of melanosome organization.
|
1 | O60315 (/ISS) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
A0A1B0GVV8 (/IDA)
A0A1B0GW50 (/IDA)
A0A1B0GWI0 (/IDA)
A0JP08 (/IDA)
G5EBU4 (/IDA)
O60315 (/IDA)
P28166 (/IDA)
P37275 (/IDA)
Q62947 (/IDA)
Q64318 (/IDA)
(1 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | A0A1B0GVV8 (/IDA) A0A1B0GW50 (/IDA) A0A1B0GWI0 (/IDA) A0JP08 (/IDA) O60315 (/IDA) P37275 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
5 | A0A1B0GVV8 (/IDA) A0A1B0GW50 (/IDA) A0A1B0GWI0 (/IDA) A0JP08 (/IDA) O60315 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P36197 (/ISS) Q60542 (/ISS) Q60542 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q64318 (/ISO) Q9R0G7 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q64318 (/ISO) Q9R0G7 (/ISO) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | O60315 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | Q9R0G7 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | P37275 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q64318 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | P37275 (/TAS) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | Q64318 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9R0G7 (/ISO) |
