The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 738: zinc finger protein Eos isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 Q9H2S9 (/ISA) Q9H2S9 (/ISA) Q9H2S9 (/ISA) Q9H2S9 (/ISA) Q9H2S9 (/ISA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
5 Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
5 Q9H2S9 (/IPI) Q9H2S9 (/IPI) Q9H2S9 (/IPI) Q9H2S9 (/IPI) Q9H2S9 (/IPI)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
5 Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
5 Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
5 Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
10 F8VPL6 (/IDA) F8VPL6 (/IDA) F8VPL6 (/IDA) F8VPL6 (/IDA) F8VPL6 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
10 F8VPL6 (/IDA) F8VPL6 (/IDA) F8VPL6 (/IDA) F8VPL6 (/IDA) F8VPL6 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA) Q9H2S9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS) Q9H2S9 (/TAS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
5 Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP) Q9H2S9 (/IMP)
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