The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 670: zinc finger protein 22

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
8 P17026 (/ISA) P17026 (/ISA) P17026 (/ISA) P17026 (/ISA) P17026 (/ISA) P17026 (/ISA) Q6ZNH5 (/ISA) Q9Y2P0 (/ISA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
7 P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) Q9ERU2 (/ISS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
6 P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
6 P17026 (/TAS) P17026 (/TAS) P17026 (/TAS) P17026 (/TAS) P17026 (/TAS) P17026 (/TAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 Q9ERU3 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
8 P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) Q9ERU2 (/NAS) Q9ERU3 (/NAS)
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
8 P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) P17026 (/NAS) Q9ERU2 (/NAS) Q9ERU3 (/NAS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) P17026 (/IDA) P17026 (/IDA) P17026 (/IDA) P17026 (/IDA)
(3 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
12 A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) A0A024R7T4 (/IDA) P17026 (/IDA) P17026 (/IDA) P17026 (/IDA) P17026 (/IDA)
(2 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) P17026 (/ISS) Q9ERU3 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9ERU3 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9ERU3 (/ISO)
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