The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 392: early growth response protein 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
19 Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA) Q06889 (/ISA)
(9 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
19 Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS) Q06889 (/NAS)
(9 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
19 Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS)
(9 more)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
2 Q9WUF2 (/ISO) Q9WUF2 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q9WUF2 (/ISO) Q9WUF2 (/ISO)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
1 Q00911 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 P43300 (/IC)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 P43300 (/IDA)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
19 Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP)
(9 more)
Cell migration involved in sprouting angiogenesis GO:0002042
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
19 Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA) Q06889 (/IDA)
(9 more)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
19 Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS)
(9 more)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
19 Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS) Q06889 (/TAS)
(9 more)
Endothelial cell chemotaxis GO:0035767
The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
19 Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP)
(9 more)
Cellular response to vascular endothelial growth factor stimulus GO:0035924
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.
19 Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP)
(9 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
19 Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP)
(9 more)
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
19 Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP) Q06889 (/IMP)
(9 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P43300 (/IDA) Q00911 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q9WUF2 (/ISO) Q9WUF2 (/ISO)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
1 P43300 (/ISO)
Cell migration involved in sprouting angiogenesis GO:0002042
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
1 P43300 (/ISO)
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
1 P43300 (/IMP)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
1 P43300 (/IMP)
Positive regulation of T cell differentiation in thymus GO:0033089
Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.
1 P43300 (/IMP)
Endothelial cell chemotaxis GO:0035767
The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 P43300 (/ISO)
Cellular response to vascular endothelial growth factor stimulus GO:0035924
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.
1 P43300 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P43300 (/ISO)
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
1 P43300 (/ISO)
Regulation of gamma-delta T cell differentiation GO:0045586
Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.
1 P43300 (/IDA)
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
1 Q00911 (/IEP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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