The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 379: Zinc finger and BTB domain-containing protein 46

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q86UZ6 (/ISA) Q8NAP8 (/ISA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8BID6 (/IPI)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of granulocyte differentiation GO:0030853
Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.
1 Q8BID6 (/IMP)
Negative regulation of macrophage differentiation GO:0045650
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.
1 Q8BID6 (/IMP)
Negative regulation of monocyte differentiation GO:0045656
Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.
1 Q8BID6 (/IMP)
Negative regulation of dendritic cell differentiation GO:2001199
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.
1 Q8BID6 (/IMP)
Positive regulation of dendritic cell differentiation GO:2001200
Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.
1 Q8BID6 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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