The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 348: zinc finger protein 260

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 Q3ZCT1 (/IPI) Q3ZCT1 (/IPI) Q3ZCT1 (/IPI) Q3ZCT1 (/IPI) Q3ZCT1 (/IPI) Q3ZCT1 (/IPI) Q8WTR7 (/IPI) Q8WTR7 (/IPI) Q8WTR7 (/IPI) Q8WTR7 (/IPI)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
8 Q3ZCT1 (/ISA) Q3ZCT1 (/ISA) Q3ZCT1 (/ISA) Q3ZCT1 (/ISA) Q3ZCT1 (/ISA) Q3ZCT1 (/ISA) Q9NQX6 (/ISA) Q9NQX6 (/ISA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q9NQX6 (/NAS) Q9NQX6 (/NAS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
4 Q8WTR7 (/TAS) Q8WTR7 (/TAS) Q8WTR7 (/TAS) Q8WTR7 (/TAS)
MRNA 3'-end processing by stem-loop binding and cleavage GO:0006398
Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.
4 Q8WTR7 (/IDA) Q8WTR7 (/IDA) Q8WTR7 (/IDA) Q8WTR7 (/IDA)
Histone mRNA metabolic process GO:0008334
The chemical reactions and pathways involving an mRNA encoding a histone.
4 Q8WTR7 (/TAS) Q8WTR7 (/TAS) Q8WTR7 (/TAS) Q8WTR7 (/TAS)
MRNA 3'-end processing by stem-loop binding and cleavage GO:0006398
Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.
1 Q8BI67 (/ISO)
MRNA 3'-end processing by stem-loop binding and cleavage GO:0006398
Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.
1 Q8BI67 (/ISS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
16 A0A024QZI1 (/IDA) A0A024QZI1 (/IDA) A0A024QZI1 (/IDA) A0A024QZI1 (/IDA) F8WEC7 (/IDA) F8WEC7 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA)
(6 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q3ZCT1 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA) Q3ZCT1 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 Q8WTR7 (/TAS) Q8WTR7 (/TAS) Q8WTR7 (/TAS) Q8WTR7 (/TAS)
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
4 Q8WTR7 (/IDA) Q8WTR7 (/IDA) Q8WTR7 (/IDA) Q8WTR7 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8BI67 (/ISO)
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
1 Q8BI67 (/ISO)
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
1 Q8BI67 (/ISS)
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