The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"2-methylcitrate dehydratase PrpD
".
FunFam 1: 2-methylcitrate dehydratase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
2-methylcitrate dehydratase activity GO:0047547
Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
|
39 |
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
(29 more) |
|
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
24 |
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
(14 more) |
|
2-methylcitrate dehydratase activity GO:0047547
Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
|
11 |
P45859 (/ISS)
P45859 (/ISS)
P45859 (/ISS)
Q8X693 (/ISS)
Q8X693 (/ISS)
Q8X693 (/ISS)
Q8X693 (/ISS)
Q8X693 (/ISS)
Q8X693 (/ISS)
Q8X693 (/ISS)
(1 more) |
|
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
7 | Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) |
|
2-methylcitrate dehydratase activity GO:0047547
Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
|
1 | C8V1C5 (/RCA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
|
24 |
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
P77243 (/IDA)
(14 more) |
|
Propionate catabolic process GO:0019543
The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.
|
14 |
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
P74840 (/IGI)
(4 more) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
14 |
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
P74840 (/IDA)
(4 more) |
|
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
|
10 | P45859 (/ISS) P45859 (/ISS) P45859 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) Q8X693 (/ISS) |
|
Propionate metabolic process GO:0019541
The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.
|
9 | Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) Q12428 (/IMP) |
|
Lysine metabolic process GO:0006553
The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.
|
1 | C8V1C5 (/RCA) |
|
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
|
1 | Q8Z903 (/ISS) |
|
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
|
1 | Q937N6 (/TAS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
9 | Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
9 | Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) Q12428 (/HDA) |