The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NADP-dependent oxidoreductase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1NADP(H)-dependent aldo-keto reductaseL-glyceraldehyde 3-phosphate reductaseAldo/keto reductaseSC:2NAD(P)H-dependent D-xylose reductase xyl1Aldo-keto reductase family 1 member B1Aldo-keto reductaseD-arabinose dehydrogenase heavy chainAldo-keto reductase family 1 member B10Aldo-keto reductase family 4 member C8voltage-gated potassium channel subunit beta-2 isoform X22,5-diketo-D-gluconic acid reductase AAldo-keto reductase family 1 member C3Oxidoreductase, aldo/keto reductaseAldo-keto reductase family 1 member A1Aldo/keto reductase family oxidoreductaseNADPH-dependent aldo-keto reductase, chloroplasticAldo/keto reductaseGlutamate--cysteine ligase regulatory subunitNADPH-dependent codeinone reductase 1-1NAD(P)-linked oxidoreductase superfamily proteinOxidoreductase, aldo/keto reductase family2,5-diketo-D-gluconic acid reductase BAflatoxin B1 aldehyde reductase member 2Glycerol dehydrogenase Gcy1NADP-dependent D-sorbitol-6-phosphate dehydrogenaseHypothetical oxidoreductase YdbCOxidoreductase, aldo/keto reductase familyaldose reductaseAryl-alcohol dehydrogenaseNADP(+)-dependent glycerol dehydrogenaseGamma-cysteine synthetase regulatory subunit, putativeAldo/keto reductaseOxidoreductase, aldo/keto reductase familyAldo-keto reductase family 1 member E2Hyperkinetic, isoform IAldo/keto reductaseChromosome 7, whole genome shotgun sequenceAldehyde reductase, putativeNADP-dependent oxidoreductase domain-containing proteinL-galactose dehydrogenase (L-GalDH)Aldo/keto reductasePutative oxidoreductasePutative aldo-keto reductaseD-arabinose 1-dehydrogenaseProbable voltage-gated potassium channel subunit betaPyridoxal reductase, chloroplasticAldose reductaseAldo-keto reductase (AKR), putativeAldo-keto reductase family 1, member B10 (aldose reductase)Putative aldo/keto reductaseProbable aldo-keto reductase 4Oxidoreductase, aldo/keto reductase family proteinAldo-keto reductase family 1 member C2Putative pyridoxal reductase (AKR8)2,5-diketo-D-gluconic acid reductase AAldo-keto oxidoreductaseL-fucose dehydrogenasePutative oxidoreductase, chloroplasticAldo-keto reductase-like proteinUncharacterized proteinAldose reductase, putativeConserved proteinPutative oxidoreductaseAldo/keto reductase, putativeOxidoreductase, aldo/keto reductase familyAldo-keto reductase 1aAryl-alcohol dehydrogenaseAldo/keto reductaseRelated to GCY1-galactose-induced protein of aldo/keto reductase family / uncharacterized proteinProtein CBG12061Aldo/keto reductaseAldose reductaseAldose reductase, putativeProstaglandin f synthase. putativeOxidoreductase, aldo/keto reductase familyGD18440Galactose dehydrogenaseAlcohol dehydrogenase, putativeAldo-keto reductase family 1 member D1glutamate--cysteine ligase regulatory subunit-likeUncharacterized oxidoreductase MSMEG_2408Oxidoreductase, aldo/keto reductase familyAryl-alcohol dehydrogenaseGlycerol dehydrogenase (GCY1), putativeUncharacterized proteinPutative sterigmatocystin biosynthesis dehydrogenase stcVAldo-keto reductase family 1 member D1Uncharacterized proteinAldo-keto reductase family 1, member B1 (aldose reductase)Aldehyde reductase proteinNADPH-dependent aldo-keto reductase, chloroplastic isoform AOxidoreductaseAldose reductaseAGAP012038-PAUncharacterized proteinAldo-keto reductase family 4 member C9Uncharacterized proteinOs10g0113375 proteinOxidoreductase, aldo/keto reductase family proteinHypothetical protein LOC594893Probable oxidoreductasePredicted proteinPutative oxidoreductaseProbable oxidoreductase (Aldo-keto reductase family protein)Predicted proteinUncharacterized proteinPutative oxidoreductase-possibly Aldo/keto reductaseChromosome 21, whole genome shotgun sequenceUncharacterized proteinUncharacterized proteinOxidoreductaseProbable L-fucose dehydrogenaseAldo/keto reductaseAldo/keto reductaseUncharacterized proteinAldehyde reductase, putativeUncharacterized proteinAKR1E2 isoform 12Uncharacterized proteinGlutamate--cysteine ligase regulatory subunitUncharacterized proteinL-galactose dehydrogenase isoform AAflatoxin B1 aldehyde reductase member 2Aldo-keto reductase family 1, member C20Galactose dehydrogenaseAldo-keto reductase family 1, member C20Glycerol dehydrogenase (GCY1), putativeNADP(+) coupled glycerol dehydrogenase (Eurofung)NADP(+) coupled glycerol dehydrogenase (Eurofung)NADP(+) coupled glycerol dehydrogenase (Eurofung)NADP(+) coupled glycerol dehydrogenase (Eurofung)Predicted proteinLOC100127714 proteinUncharacterized proteinUncharacterized proteindTDP-4-keto-L-6-deoxy-hexose 2,3-reductase-putative a NADP-dependent oxidoreductasePredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized oxidoreductase C215.11cUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized oxidoreductase C28F2.05Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinPredicted proteinUncharacterized proteinAldo-keto reductase, putativeUncharacterized proteinAGAP012851-PAPotassium voltage-gated channel, shaker-related subfamily, beta member 2 bMIP04347pOxidoreductase, aldo/keto reductase family proteinPredicted proteinOxidoreductase, aldo/keto reductase family proteinGlutamate--cysteine ligase regulatory subunit-like ProteinPutative glutamate--cysteine ligase regulatory subunitUncharacterized proteinUncharacterized proteinOxidoreductase, aldo/keto reductase family proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinOxidoreductase, aldo/keto reductase family proteinOxidoreductase, aldo/keto reductase family proteinOxidoreductase, aldo/keto reductase family proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAldo-keto reductase, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAlcohol dehydrogenase [NADP(+)] A-like ProteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAldo-keto reductase family 1, member C19Aldo-keto reductase, putativeUncharacterized proteinUncharacterized proteinGalactose dehydrogenaseUncharacterized proteinUncharacterized proteinOs05g0456200 proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinBifunctional protein STORRUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSorting nexin 2BAldo-keto-reductase-like proteinAldo-keto-reductase-like proteinAldo-keto-reductase-like proteinUncharacterized proteinUncharacterized protein
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FunFam 93: Aldose reductase

There are 0 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

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