The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CBS-domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 52: Cystathionine beta-synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
5 P32582 (/HDA) P32582 (/HDA) P32582 (/HDA) P32582 (/HDA) P32582 (/HDA)
Cystathionine beta-synthase activity GO:0004122
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
5 P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA)
Cystathionine beta-synthase activity GO:0004122
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
5 P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP)
Cystathionine beta-synthase activity GO:0004122
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
1 P46794 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cysteine biosynthetic process from serine GO:0006535
The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.
5 P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA)
Traversing start control point of mitotic cell cycle GO:0007089
A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
5 P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP)
Cysteine biosynthetic process via cystathionine GO:0019343
The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.
5 P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP)
Transsulfuration GO:0019346
The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
5 P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP) P32582 (/IMP)
Hydrogen sulfide biosynthetic process GO:0070814
The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
5 P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA)
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
1 P46794 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P32582 (/HDA) P32582 (/HDA) P32582 (/HDA) P32582 (/HDA) P32582 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P32582 (/HDA) P32582 (/HDA) P32582 (/HDA) P32582 (/HDA) P32582 (/HDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
5 P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA) P32582 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q6FVB8 (/IDA) Q6FVB8 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P46794 (/ISS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...