The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homing endonucleases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Protein RecA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Recombinase activity GO:0000150
Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
Endodeoxyribonuclease activity GO:0004520
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P9WHJ3 (/IPI) P9WHJ3 (/IPI) P9WHJ3 (/IPI) P9WHJ3 (/IPI) P9WHJ3 (/IPI) P9WHJ3 (/IPI) P9WHJ3 (/IPI) P9WHJ3 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Recombinational repair GO:0000725
A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA.
8 P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
8 P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
8 P9WHJ3 (/IGI) P9WHJ3 (/IGI) P9WHJ3 (/IGI) P9WHJ3 (/IGI) P9WHJ3 (/IGI) P9WHJ3 (/IGI) P9WHJ3 (/IGI) P9WHJ3 (/IGI)
UV protection GO:0009650
Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.
8 P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP) P9WHJ3 (/IMP)
Strand invasion GO:0042148
The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
8 P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA) P9WHJ3 (/IDA)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
8 P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP) P9WHJ3 (/IEP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P9WHJ3 (/HDA) P9WHJ3 (/HDA) P9WHJ3 (/HDA) P9WHJ3 (/HDA) P9WHJ3 (/HDA) P9WHJ3 (/HDA) P9WHJ3 (/HDA) P9WHJ3 (/HDA)