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CATH Superfamily 3.10.250.10

SRCR-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SRCR-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Lysyl oxidase homolog 2

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-lysine 6-oxidase. [EC: 1.4.3.13]
[Protein]-L-lysine + O(2) + H(2)O = [protein]-(S)-2-amino-6-oxohexanoate + NH(3) + H(2)O(2).
  • Also acts on protein 5-hydroxylysine.
  • Catalyzes the final known enzymic step required for collagen and elastin cross-linking in the biosynthesis of normal mature extracellular matrices.
  • These reactions play an important role for the development, elasticity and extensibility of connective tissue.
  • Also active on free amines, such as cadaverine or benzylamine.
 14 A1L1V4 A6H737 B4F6N6 B5DF27 B8A4W9 E1C3U7 F1QQC3 F1RD85 P58022 P58215
(4 more...)
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