The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Alpha carbonic anhydrase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Carbonic anhydrase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
21 P00915 (/TAS) P00915 (/TAS) P00918 (/TAS) P00918 (/TAS) P07451 (/TAS) P07451 (/TAS) P14141 (/TAS) P35218 (/TAS) P43166 (/TAS) P43166 (/TAS)
(11 more)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
10 A0A385NIA3 (/IMP) F1R454 (/IMP) P00915 (/IMP) P00915 (/IMP) P00918 (/IMP) P00918 (/IMP) P00920 (/IMP) Q6PFU7 (/IMP) Q92051 (/IMP) Q9ERQ8 (/IMP)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
8 A0A1D5NTS2 (/IDA) P00920 (/IDA) P07630 (/IDA) P23589 (/IDA) P27139 (/IDA) P43165 (/IDA) Q9D6N1 (/IDA) Q9QZA0 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P00915 (/IPI) P00915 (/IPI) P00918 (/IPI) P00918 (/IPI) P27139 (/IPI)
Arylesterase activity GO:0004064
Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.
4 P00915 (/IMP) P00915 (/IMP) P00918 (/IMP) P00918 (/IMP)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
4 A0A385NIA3 (/IGI) F1R454 (/IGI) Q6PFU7 (/IGI) Q92051 (/IGI)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
3 P00920 (/ISO) P13634 (/ISO) P23589 (/ISO)
Arylesterase activity GO:0004064
Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.
2 P00920 (/ISO) P13634 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 P00918 (/IDA) P00918 (/IDA)
Hydro-lyase activity GO:0016836
Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2 P00915 (/IDA) P00915 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 P00920 (/ISO)
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
1 P16015 (/IDA)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
1 P14141 (/IDA)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
1 P16015 (/ISO)
Hydro-lyase activity GO:0016836
Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
1 P13634 (/ISO)

There are 52 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
21 P00915 (/TAS) P00915 (/TAS) P00918 (/TAS) P00918 (/TAS) P07451 (/TAS) P07451 (/TAS) P35218 (/TAS) P43166 (/TAS) P43166 (/TAS) P43166 (/TAS)
(11 more)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
6 P00918 (/ISS) P00918 (/ISS) P00919 (/ISS) P00921 (/ISS) P00922 (/ISS) P27139 (/ISS)
Positive regulation of dipeptide transmembrane transport GO:2001150
Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.
6 P00918 (/ISS) P00918 (/ISS) P00919 (/ISS) P00921 (/ISS) P00922 (/ISS) P27139 (/ISS)
Carbon dioxide transport GO:0015670
The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 A0A385NIA3 (/IMP) F1R454 (/IMP) P00920 (/IMP) Q6PFU7 (/IMP) Q92051 (/IMP)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
5 P00919 (/ISS) P00920 (/ISS) P00921 (/ISS) P00922 (/ISS) P27139 (/ISS)
Regulation of anion transport GO:0044070
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 P00919 (/ISS) P00920 (/ISS) P00921 (/ISS) P00922 (/ISS) P27139 (/ISS)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
4 A0A385NIA3 (/IMP) F1R454 (/IMP) Q68YC2 (/IMP) Q6PFU7 (/IMP)
Carbon dioxide transport GO:0015670
The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 A0A385NIA3 (/IGI) F1R454 (/IGI) Q6PFU7 (/IGI) Q92051 (/IGI)
Hypotonic salinity response GO:0042539
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
4 A0A385NIA3 (/IDA) F1R454 (/IDA) Q6PFU7 (/IDA) Q92051 (/IDA)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 A0A385NIA3 (/IMP) F1R454 (/IMP) Q6PFU7 (/IMP)
Positive regulation of cellular pH reduction GO:0032849
Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
3 P00920 (/IMP) P27139 (/IMP) Q9ERQ8 (/IMP)
Cellular response to xenobiotic stimulus GO:0071466
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
3 A0A385NIA3 (/IDA) F1R454 (/IDA) Q6PFU7 (/IDA)
Sodium ion import across plasma membrane GO:0098719
The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.
3 A0A385NIA3 (/IMP) F1R454 (/IMP) Q6PFU7 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
2 P16015 (/IEP) Q9QZA0 (/IEP)
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
2 P00920 (/IGI) Q9ERQ8 (/IGI)
Interleukin-12-mediated signaling pathway GO:0035722
A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P00915 (/TAS) P00915 (/TAS)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
2 P00918 (/IDA) P00918 (/IDA)
Regulation of anion transport GO:0044070
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P00918 (/IDA) P00918 (/IDA)
Ion homeostasis GO:0050801
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
2 A0A0J9YJ49 (/IMP) A8KB74 (/IMP)
Regulation of chloride transport GO:2001225
Any process that modulates the frequency, rate or extent of chloride transport.
2 P00920 (/IMP) Q9ERQ8 (/IMP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 P27139 (/IEP)
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
1 P00920 (/IMP)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
1 P23589 (/TAS)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
1 P00920 (/IC)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P14141 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P16015 (/ISO)
Response to pH GO:0009268
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
1 P27139 (/IEP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P27139 (/IEP)
Response to carbon dioxide GO:0010037
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
1 Q68YC2 (/IDA)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
1 P27139 (/IEP)
Carbon dioxide transport GO:0015670
The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P00920 (/IC)
Osteoclast differentiation GO:0030316
The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
1 P27139 (/TAS)
Regulation of cellular pH GO:0030641
Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.
1 P27139 (/TAS)
Positive regulation of cellular pH reduction GO:0032849
Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
1 P00920 (/ISO)
Positive regulation of urine volume GO:0035810
Any process that increases the amount of urine excreted from the body over a unit of time.
1 Q68YC2 (/IMP)
Regulation of renal sodium excretion GO:0035813
Any process that modulates the amount of sodium excreted in urine over a unit of time.
1 Q68YC2 (/IMP)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
1 P00920 (/ISO)
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
1 P27139 (/IEP)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 P27139 (/IEP)
Regulation of anion transport GO:0044070
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P00920 (/ISO)
Regulation of bone resorption GO:0045124
Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).
1 P27139 (/TAS)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 P14141 (/IEP)
Positive regulation of osteoclast differentiation GO:0045672
Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.
1 P27139 (/IMP)
Positive regulation of osteoclast differentiation GO:0045672
Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.
1 P00920 (/ISO)
Positive regulation of bone resorption GO:0045780
Any process that activates or increases the frequency, rate or extent of bone resorption.
1 P27139 (/IMP)
Positive regulation of bone resorption GO:0045780
Any process that activates or increases the frequency, rate or extent of bone resorption.
1 P00920 (/ISO)
Secretion GO:0046903
The controlled release of a substance by a cell or a tissue.
1 P00920 (/IMP)
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
1 P27139 (/IEP)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 P00920 (/IMP)
Cellular response to carbon dioxide GO:0071244
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
1 P07630 (/IDA)
Cellular response to fluid shear stress GO:0071498
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
1 P27139 (/IEP)
Positive regulation of dipeptide transmembrane transport GO:2001150
Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.
1 P00920 (/IMP)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
17 P00915 (/TAS) P00915 (/TAS) P00918 (/TAS) P00918 (/TAS) P07451 (/TAS) P07451 (/TAS) P43166 (/TAS) P43166 (/TAS) P43166 (/TAS) P43166 (/TAS)
(7 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 A0A024RBW9 (/IDA) A0A024RBW9 (/IDA) A0A024RBW9 (/IDA) P23589 (/IDA) P43165 (/IDA) Q9QZA0 (/IDA) Q9Y2D0 (/IDA) Q9Y2D0 (/IDA) Q9Y2D0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P00919 (/ISS) P00920 (/ISS) P00921 (/ISS) P00922 (/ISS) P07630 (/ISS) P27139 (/ISS) Q8UWA5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P00919 (/ISS) P00920 (/ISS) P00921 (/ISS) P00922 (/ISS) P07630 (/ISS) Q8UWA5 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P00920 (/IDA) P14141 (/IDA) P16015 (/IDA) Q9D6N1 (/IDA) Q9ERQ8 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P00918 (/IDA) P00918 (/IDA) P07630 (/IDA) P27139 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 P35218 (/TAS) Q9Y2D0 (/TAS) Q9Y2D0 (/TAS) Q9Y2D0 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
4 P35218 (/TAS) Q9Y2D0 (/TAS) Q9Y2D0 (/TAS) Q9Y2D0 (/TAS)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
4 P00918 (/IDA) P00918 (/IDA) P27139 (/IDA) Q68YC2 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 P00915 (/HDA) P00915 (/HDA) P00918 (/HDA) P00918 (/HDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 A0A1D5NTS2 (/IDA) P07630 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P23589 (/HDA) Q9QZA0 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P23589 (/ISO) Q9QZA0 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P00918 (/IDA) P00918 (/IDA)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
2 P00920 (/IDA) Q9D6N1 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P27139 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P00920 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P00920 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 P35218 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P16015 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P00920 (/ISO)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
1 P27139 (/IDA)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
1 P00920 (/ISO)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 P27139 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 P00920 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P27139 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P00920 (/ISO)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
1 P00920 (/HDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q9D6N1 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
1 P00920 (/ISO)
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