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CATH Superfamily 3.10.20.90

Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 83: Trans-2,3-enoyl-CoA reductase b

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Very-long-chain enoyl-CoA reductase. [EC: 1.3.1.93]
A very-long-chain acyl-CoA + NADP(+) = a very-long-chain trans-2,3- dehydroacyl-CoA + NADPH.
  • This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs.
  • Cf. EC 2.3.1.199, EC 1.1.1.330 and EC 4.2.1.134.
  • Formerly EC 2.3.1.119.
 42 A0A2I2UDC2 A0A2I2UDC2 A0A2I2UDC2 A0A2I2UDC2 A0A2I2UDC2 A0A2I2UDC2 A0A2R9AIJ2 A0A2R9AIJ2 A0A2R9AIJ2 A0A2R9AIJ2
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