The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Doublecortin domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Oxygen-regulated protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P56715 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
1 P56716 (/IDA)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Axoneme assembly GO:0035082
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Photoreceptor cell outer segment organization GO:0035845
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Photoreceptor cell development GO:0042461
Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Retinal rod cell development GO:0046548
Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
3 A0A286YAD5 (/IMP) E7F630 (/IMP) P56716 (/IMP)
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
2 A0A286YAD5 (/IGI) E7F630 (/IGI)
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
2 A0A286YAD5 (/IMP) E7F630 (/IMP)
Convergent extension GO:0060026
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.
2 A0A286YAD5 (/IGI) E7F630 (/IGI)
Convergent extension GO:0060026
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.
2 A0A286YAD5 (/IMP) E7F630 (/IMP)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
2 A0A286YAD5 (/IGI) E7F630 (/IGI)
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
1 P56716 (/TAS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 P56715 (/TAS)
Phototransduction, visible light GO:0007603
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
1 P56715 (/TAS)
Axoneme assembly GO:0035082
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
1 P56716 (/IDA)
Photoreceptor cell outer segment organization GO:0035845
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
1 P56716 (/IDA)
Photoreceptor cell development GO:0042461
Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
1 P56716 (/IMP)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
1 P56716 (/IMP)
Retinal rod cell development GO:0046548
Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.
1 P56716 (/IDA)
Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
1 P56716 (/IDA)
Microtubule polymerization GO:0046785
The addition of tubulin heterodimers to one or both ends of a microtubule.
1 P56716 (/TAS)
Retina morphogenesis in camera-type eye GO:0060042
The process in which the anatomical structure of the retina is generated and organized.
1 P56716 (/IMP)
Cellular response to light stimulus GO:0071482
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 P56716 (/IMP)
Positive regulation of non-motile cilium assembly GO:1902857
Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.
1 P56716 (/IDA)
Positive regulation of non-motile cilium assembly GO:1902857
Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.
1 P56716 (/IGI)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
5 P56715 (/ISS) Q8MJ03 (/ISS) Q8MJ04 (/ISS) Q8MJ05 (/ISS) Q8MJ06 (/ISS)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
2 P56715 (/IDA) P56716 (/IDA)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
2 Q8MJ03 (/ISS) Q8MJ06 (/ISS)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
2 P56715 (/IDA) P56716 (/IDA)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
1 P56716 (/IDA)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1 P56716 (/ISO)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
1 P56716 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 P56716 (/IDA)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
1 P56716 (/IDA)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
1 P56716 (/ISO)
Ciliary tip GO:0097542
Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
1 P56716 (/IDA)
Photoreceptor cell cilium GO:0097733
A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.
1 P56716 (/IDA)
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