The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin Conjugating Enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 70: RWD domain containing 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9Y3V2 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
4 A3KN24 (/ISS) P0C7N0 (/ISS) Q5RDC7 (/ISS) Q8VIL2 (/ISS)
Positive regulation of protein sumoylation GO:0033235
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
4 A3KN24 (/ISS) P0C7N0 (/ISS) Q5RDC7 (/ISS) Q8VIL2 (/ISS)
Positive regulation of hypoxia-inducible factor-1alpha signaling pathway GO:1902073
Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
4 A3KN24 (/ISS) P0C7N0 (/ISS) Q5RDC7 (/ISS) Q8VIL2 (/ISS)
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
1 Q9Y3V2 (/IDA)
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
1 Q8VIL2 (/ISO)
Positive regulation of protein sumoylation GO:0033235
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
1 Q9Y3V2 (/IDA)
Positive regulation of protein sumoylation GO:0033235
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
1 Q8VIL2 (/ISO)
Positive regulation of hypoxia-inducible factor-1alpha signaling pathway GO:1902073
Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
1 Q9Y3V2 (/IDA)
Positive regulation of hypoxia-inducible factor-1alpha signaling pathway GO:1902073
Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
1 Q8VIL2 (/IMP)
Positive regulation of hypoxia-inducible factor-1alpha signaling pathway GO:1902073
Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
1 Q8VIL2 (/ISO)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.