The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Mannose-Binding Protein A, subunit A
".
FunFam 77: Killer cell lectin-like receptor subfamily B membe...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
10 | P27812 (/IDA) P27812 (/IDA) P27814 (/IDA) P27814 (/IDA) Q0ZUP1 (/IDA) Q0ZUP1 (/IDA) Q8VD98 (/IDA) Q8VD98 (/IDA) Q99JB4 (/IDA) Q99JB4 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | P27812 (/IPI) P27812 (/IPI) Q0ZUP1 (/IPI) Q0ZUP1 (/IPI) Q12918 (/IPI) Q8VD98 (/IPI) Q8VD98 (/IPI) Q99JB4 (/IPI) Q99JB4 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
6 | P27812 (/IDA) P27812 (/IDA) P27814 (/IDA) P27814 (/IDA) Q99JB4 (/IDA) Q99JB4 (/IDA) |
|
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
1 | Q12918 (/TAS) |
|
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
|
1 | Q12918 (/TAS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of natural killer cell mediated cytotoxicity GO:0045953
Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
|
4 | P27812 (/IDA) P27812 (/IDA) Q99JB4 (/IDA) Q99JB4 (/IDA) |
|
Negative regulation of natural killer cell mediated cytotoxicity GO:0045953
Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
|
4 | P27812 (/IGI) P27812 (/IGI) Q99JB4 (/IGI) Q99JB4 (/IGI) |
|
Natural killer cell activation GO:0030101
The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
|
2 | P27814 (/IDA) P27814 (/IDA) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
2 | P27814 (/IDA) P27814 (/IDA) |
|
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q12918 (/TAS) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q12918 (/TAS) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
10 | P27811 (/IDA) P27811 (/IDA) P27812 (/IDA) P27812 (/IDA) P27814 (/IDA) P27814 (/IDA) Q8VD98 (/IDA) Q8VD98 (/IDA) Q99JB4 (/IDA) Q99JB4 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | P27812 (/IDA) P27812 (/IDA) P27814 (/IDA) P27814 (/IDA) Q99JB4 (/IDA) Q99JB4 (/IDA) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
6 | P27812 (/IDA) P27812 (/IDA) P27814 (/IDA) P27814 (/IDA) Q99JB4 (/IDA) Q99JB4 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
4 | P27814 (/IDA) P27814 (/IDA) Q8VD98 (/IDA) Q8VD98 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q12918 (/TAS) |