The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mannose-Binding Protein A, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 64: Natural killer cells antigen CD94

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
1 Q13241 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q13241 (/IPI)
MHC class I protein complex binding GO:0023024
Interacting selectively and non-covalently with the class I major histocompatibility complex.
1 Q13241 (/IPI)
MHC class I protein complex binding GO:0023024
Interacting selectively and non-covalently with the class I major histocompatibility complex.
1 O54707 (/ISO)
MHC class Ib protein binding, via antigen binding groove GO:0023030
Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the antigen binding groove.
1 Q13241 (/IPI)
MHC class Ib protein binding, via antigen binding groove GO:0023030
Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the antigen binding groove.
1 O54707 (/ISO)
Protein antigen binding GO:1990405
Interacting selectively and non-covalently with a protein antigen.
1 Q13241 (/IDA)
Protein antigen binding GO:1990405
Interacting selectively and non-covalently with a protein antigen.
1 O54707 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Natural killer cell mediated immunity GO:0002228
The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
1 Q13241 (/IDA)
Natural killer cell mediated immunity GO:0002228
The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
1 O54707 (/ISO)
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
1 Q13241 (/TAS)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
1 Q13241 (/TAS)
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
1 Q13241 (/TAS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q13241 (/TAS)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 O54707 (/IDA)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q13241 (/IDA)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 O54707 (/ISO)
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