The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 62: Fibroblast growth factor 23

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9EPC2 (/IPI) Q9EPC2 (/IPI) Q9GZV9 (/IPI)
Type 1 fibroblast growth factor receptor binding GO:0005105
Interacting selectively and non-covalently with the type 1 fibroblast growth factor receptor (FGFR1).
2 Q9EPC2 (/IPI) Q9EPC2 (/IPI)
Fibroblast growth factor receptor binding GO:0005104
Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR).
1 Q8VI82 (/TAS)
Showing 1 to 3 of 3 entries

There are 34 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Negative regulation of hormone secretion GO:0046888
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
3 Q9EPC2 (/ISS) Q9EPC2 (/ISS) Q9GZV9 (/ISS)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
2 Q9EPC2 (/IDA) Q9EPC2 (/IDA)
Regulation of phosphate transport GO:0010966
Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9EPC2 (/ISO) Q9EPC2 (/ISO)
Positive regulation of vitamin D 24-hydroxylase activity GO:0010980
Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
2 Q9EPC2 (/ISO) Q9EPC2 (/ISO)
Regulation of bone mineralization GO:0030500
Any process that modulates the frequency, rate or extent of bone mineralization.
2 Q9EPC2 (/IMP) Q9EPC2 (/IMP)
Negative regulation of bone mineralization GO:0030502
Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.
2 Q9EPC2 (/ISO) Q9EPC2 (/ISO)
Cellular phosphate ion homeostasis GO:0030643
Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.
2 Q9EPC2 (/IMP) Q9EPC2 (/IMP)
Vitamin D catabolic process GO:0042369
The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
2 Q9EPC2 (/ISO) Q9EPC2 (/ISO)
Negative regulation of osteoblast differentiation GO:0045668
Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.
2 Q9EPC2 (/ISO) Q9EPC2 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9EPC2 (/IDA) Q9EPC2 (/IDA)
Showing 1 to 10 of 34 entries

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q8VI82 (/IDA) Q9EPC2 (/IDA) Q9EPC2 (/IDA) Q9GZV9 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 Q9EPC2 (/ISO) Q9EPC2 (/ISO)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q9GZV9 (/TAS)
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
1 Q9GZV9 (/TAS)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
1 Q9GZV9 (/TAS)
Showing 1 to 5 of 5 entries
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