The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PLAT/LH2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Arachidonate 5-lipoxygenase a

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 43 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arachidonate 12-lipoxygenase activity GO:0004052
Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
13 O70582 (/IDA) O70582 (/IDA) P12530 (/IDA) P16050 (/IDA) P16469 (/IDA) P18054 (/IDA) P27479 (/IDA) P39654 (/IDA) P39654 (/IDA) P39655 (/IDA)
(3 more)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
13 P12527 (/ISS) P12530 (/ISS) P16050 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) P48999 (/ISS) P51399 (/ISS) P51399 (/ISS) Q02759 (/ISS)
(3 more)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 O75342 (/IPI) P09917 (/IPI) P12527 (/IPI) P16050 (/IPI) P18054 (/IPI) P48999 (/IPI) Q9BYJ1 (/IPI)
Arachidonate 12-lipoxygenase activity GO:0004052
Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
6 O70582 (/ISO) O70582 (/ISO) P39654 (/ISO) P39654 (/ISO) P39655 (/ISO) P39655 (/ISO)
Arachidonate 12-lipoxygenase activity GO:0004052
Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
6 P12530 (/ISS) P39655 (/ISS) P39655 (/ISS) Q2KMM4 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Arachidonate 15-lipoxygenase activity GO:0050473
Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
6 O15296 (/IDA) P16050 (/IDA) P39654 (/IDA) P39654 (/IDA) Q02759 (/IDA) Q8K4F2 (/IDA)
Arachidonate 15-lipoxygenase activity GO:0050473
Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
5 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Arachidonate 5-lipoxygenase activity GO:0004051
Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.
3 A0A2R8RVT0 (/IDA) B8A697 (/IDA) P09917 (/IDA)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
3 O15296 (/IDA) P09917 (/IDA) P16469 (/IDA)
Linoleate 13S-lipoxygenase activity GO:0016165
Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
3 O35936 (/ISO) P39655 (/ISO) P39655 (/ISO)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
3 O75342 (/IDA) Q7T2A9 (/IDA) Q9BYJ1 (/IDA)
Hepoxilin-epoxide hydrolase activity GO:0047977
Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.
3 P18054 (/ISS) P39655 (/ISS) P39655 (/ISS)
Arachidonate 15-lipoxygenase activity GO:0050473
Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
3 O35936 (/ISO) P39654 (/ISO) P39654 (/ISO)
Hepoxilin A3 synthase activity GO:0051120
Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
3 Q02759 (/IDA) Q9BYJ1 (/IDA) Q9WV07 (/IDA)
Hepoxilin A3 synthase activity GO:0051120
Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
3 P39654 (/ISO) P39654 (/ISO) Q9WV07 (/ISO)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2 O70582 (/IDA) O70582 (/IDA)
Arachidonate 5-lipoxygenase activity GO:0004051
Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.
2 P51399 (/ISS) P51399 (/ISS)
Arachidonate 12-lipoxygenase activity GO:0004052
Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
2 O75342 (/IMP) Q7T2A9 (/IMP)
Leukotriene-C4 synthase activity GO:0004464
Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4).
2 A0A2R8RVT0 (/IDA) B8A697 (/IDA)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
2 O35936 (/ISO) P48999 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 O15296 (/IDA) Q7T2A9 (/IDA)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
2 P39654 (/ISO) P39654 (/ISO)
Arachidonic acid monooxygenase activity GO:0008391
Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
2 A0A2R8RVT0 (/IDA) B8A697 (/IDA)
Linoleate 13S-lipoxygenase activity GO:0016165
Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
2 O15296 (/IDA) P18054 (/IDA)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
2 O70582 (/ISO) O70582 (/ISO)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
2 D3ZKX9 (/ISS) Q9WV07 (/ISS)
Hepoxilin-epoxide hydrolase activity GO:0047977
Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.
2 P39654 (/ISO) P39654 (/ISO)
Linoleate 9S-lipoxygenase activity GO:1990136
Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
2 O70582 (/IDA) O70582 (/IDA)
Linoleate 9S-lipoxygenase activity GO:1990136
Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
2 O75342 (/ISS) Q2KMM4 (/ISS)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
1 Q9WV07 (/ISA)
Arachidonate 5-lipoxygenase activity GO:0004051
Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.
1 P48999 (/ISO)
Arachidonate 5-lipoxygenase activity GO:0004051
Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.
1 P09917 (/TAS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 O35936 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q8K4F2 (/ISS)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
1 P16050 (/IDA)
Potassium channel inhibitor activity GO:0019870
Stops, prevents, or reduces the activity of a potassium channel.
1 Q02759 (/TAS)
Arachidonate 8(S)-lipoxygenase activity GO:0036403
Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
1 O35936 (/IDA)
Hepoxilin-epoxide hydrolase activity GO:0047977
Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.
1 Q02759 (/IDA)
Arachidonate 15-lipoxygenase activity GO:0050473
Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
1 P16050 (/NAS)
Arachidonate 15-lipoxygenase activity GO:0050473
Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
1 P16050 (/TAS)
Hepoxilin A3 synthase activity GO:0051120
Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
1 D3ZKX9 (/ISS)
Hepoxilin A3 synthase activity GO:0051120
Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
1 Q9BYJ1 (/TAS)

There are 167 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
23 A0A2R8RVT0 (/IDA) B8A697 (/IDA) D3ZKX9 (/IDA) D3ZQF9 (/IDA) F1LQ70 (/IDA) O15296 (/IDA) O35936 (/IDA) O70582 (/IDA) O70582 (/IDA) P12530 (/IDA)
(13 more)
Lipoxygenase pathway GO:0019372
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
16 D3ZQF9 (/IDA) F1LQ70 (/IDA) O35936 (/IDA) O75342 (/IDA) P12530 (/IDA) P16050 (/IDA) P16469 (/IDA) P18054 (/IDA) P27479 (/IDA) P39654 (/IDA)
(6 more)
Hepoxilin biosynthetic process GO:0051122
The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
13 O15296 (/ISS) O70582 (/ISS) O70582 (/ISS) O75342 (/ISS) P12530 (/ISS) P16050 (/ISS) P18054 (/ISS) P39654 (/ISS) P39654 (/ISS) P39655 (/ISS)
(3 more)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
10 O35936 (/ISO) O70582 (/ISO) O70582 (/ISO) P39654 (/ISO) P39654 (/ISO) P39655 (/ISO) P39655 (/ISO) P55249 (/ISO) P55249 (/ISO) Q9WV07 (/ISO)
Lipoxygenase pathway GO:0019372
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
10 O35936 (/ISO) O70582 (/ISO) O70582 (/ISO) P39654 (/ISO) P39654 (/ISO) P39655 (/ISO) P39655 (/ISO) P55249 (/ISO) P55249 (/ISO) Q9WV07 (/ISO)
Lipoxin A4 biosynthetic process GO:2001303
The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
10 F1LQ70 (/ISS) P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) P39655 (/ISS) P39655 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Lipoxygenase pathway GO:0019372
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
8 D3ZKX9 (/ISS) O70582 (/ISS) O70582 (/ISS) P12530 (/ISS) Q2KMM4 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS) Q9WV07 (/ISS)
Cellular response to interleukin-13 GO:0035963
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
8 O35936 (/IDA) O70582 (/IDA) O70582 (/IDA) P12530 (/IDA) P16469 (/IDA) P18054 (/IDA) Q9BYJ1 (/IDA) Q9WV07 (/IDA)
Hepoxilin biosynthetic process GO:0051122
The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
8 O35936 (/ISO) O70582 (/ISO) O70582 (/ISO) P39654 (/ISO) P39654 (/ISO) P39655 (/ISO) P39655 (/ISO) Q9WV07 (/ISO)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Negative regulation of adaptive immune response GO:0002820
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Phosphatidylethanolamine biosynthetic process GO:0006646
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
7 O75342 (/IMP) P39654 (/IMP) P39654 (/IMP) P39655 (/IMP) P39655 (/IMP) P55249 (/IMP) P55249 (/IMP)
Lipoxygenase pathway GO:0019372
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
7 O75342 (/IMP) P39654 (/IMP) P39654 (/IMP) P39655 (/IMP) P39655 (/IMP) P55249 (/IMP) P55249 (/IMP)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Regulation of peroxisome proliferator activated receptor signaling pathway GO:0035358
Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Hepoxilin biosynthetic process GO:0051122
The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
7 D3ZKX9 (/IDA) F1LQ70 (/IDA) Q02759 (/IDA) Q2KMM4 (/IDA) Q8K4F2 (/IDA) Q9BYJ1 (/IDA) Q9WV07 (/IDA)
Regulation of engulfment of apoptotic cell GO:1901074
Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Lipoxygenase pathway GO:0019372
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
6 O15296 (/TAS) O75342 (/TAS) P09917 (/TAS) P16050 (/TAS) P18054 (/TAS) Q9BYJ1 (/TAS)
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
6 D3ZKX9 (/ISS) F1LQ70 (/ISS) O75342 (/ISS) P39655 (/ISS) P39655 (/ISS) Q2KMM4 (/ISS)
Establishment of skin barrier GO:0061436
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
6 D3ZKX9 (/ISS) F1LQ70 (/ISS) O75342 (/ISS) P18054 (/ISS) Q2KMM4 (/ISS) Q9BYJ1 (/ISS)
Sphingolipid metabolic process GO:0006665
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
5 D3ZKX9 (/ISS) O70582 (/ISS) O70582 (/ISS) Q2KMM4 (/ISS) Q9WV07 (/ISS)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
5 O75342 (/ISS) P12530 (/ISS) P18054 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Establishment of skin barrier GO:0061436
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
5 O70582 (/IMP) O70582 (/IMP) P39655 (/IMP) P39655 (/IMP) Q9WV07 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 O70582 (/ISO) O70582 (/ISO) P39655 (/ISO) P39655 (/ISO)
Ceramide biosynthetic process GO:0046513
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
4 D3ZKX9 (/ISS) O75342 (/ISS) Q2KMM4 (/ISS) Q9BYJ1 (/ISS)
Sphingolipid metabolic process GO:0006665
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
3 O70582 (/ISO) O70582 (/ISO) Q9WV07 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
3 O70582 (/ISS) O70582 (/ISS) Q2KMM4 (/ISS)
Negative regulation of muscle cell apoptotic process GO:0010656
Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
3 F1LQ70 (/ISS) P39655 (/ISS) P39655 (/ISS)
Leukotriene biosynthetic process GO:0019370
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
3 P12527 (/ISS) P51399 (/ISS) P51399 (/ISS)
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
3 P39655 (/ISS) P39655 (/ISS) Q02759 (/ISS)
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
3 P09917 (/TAS) P16050 (/TAS) P18054 (/TAS)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
3 O70582 (/ISS) O70582 (/ISS) Q2KMM4 (/ISS)
Ceramide biosynthetic process GO:0046513
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
3 O70582 (/IMP) O70582 (/IMP) Q9WV07 (/IMP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
3 O70582 (/ISS) O70582 (/ISS) Q2KMM4 (/ISS)
Positive regulation of mucus secretion GO:0070257
Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
3 O70582 (/ISS) O70582 (/ISS) Q2KMM4 (/ISS)
Leukotriene A4 metabolic process GO:1901751
The chemical reactions and pathways involving leukotriene A4.
3 F1LQ70 (/ISS) P39655 (/ISS) P39655 (/ISS)
Lipoxin B4 biosynthetic process GO:2001306
The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
3 F1LQ70 (/ISS) P39655 (/ISS) P39655 (/ISS)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
2 P39654 (/IMP) P39654 (/IMP)
Negative regulation of adaptive immune response GO:0002820
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
2 P39654 (/IMP) P39654 (/IMP)
Protein lipidation GO:0006497
The covalent attachment of lipid groups to an amino acid in a protein.
2 O70582 (/IMP) O70582 (/IMP)
Protein lipidation GO:0006497
The covalent attachment of lipid groups to an amino acid in a protein.
2 O75342 (/ISS) Q2KMM4 (/ISS)
Phosphatidylethanolamine biosynthetic process GO:0006646
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
2 P39654 (/IMP) P39654 (/IMP)
Sphingolipid metabolic process GO:0006665
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
2 O75342 (/IDA) Q9BYJ1 (/IDA)
Leukotriene metabolic process GO:0006691
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2 P09917 (/TAS) P16050 (/TAS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 F1LQ70 (/IMP) O75342 (/IMP)
Negative regulation of muscle cell apoptotic process GO:0010656
Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
2 P39655 (/ISO) P39655 (/ISO)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
2 P39654 (/ISO) P39654 (/ISO)
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
2 P39655 (/ISO) P39655 (/ISO)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P09917 (/TAS) P16050 (/TAS)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 D3ZKX9 (/IMP) P12527 (/IMP)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 P48999 (/ISO) Q9WV07 (/ISO)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 Q9BYJ1 (/ISS) Q9WV07 (/ISS)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
2 P16050 (/NAS) Q02759 (/NAS)
Leukotriene biosynthetic process GO:0019370
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2 P09917 (/IDA) P48999 (/IDA)
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
2 P39655 (/ISO) P39655 (/ISO)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
2 P39654 (/IMP) P39654 (/IMP)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
2 P39654 (/IMP) P39654 (/IMP)
Positive regulation of heterotypic cell-cell adhesion GO:0034116
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
2 P39654 (/ISO) P39654 (/ISO)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
2 P39654 (/IMP) P39654 (/IMP)
Peroxisome proliferator activated receptor signaling pathway GO:0035357
The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.
2 D3ZKX9 (/ISS) Q9BYJ1 (/ISS)
Regulation of peroxisome proliferator activated receptor signaling pathway GO:0035358
Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
2 P39654 (/IMP) P39654 (/IMP)
Cellular response to interleukin-13 GO:0035963
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
2 P39654 (/ISO) P39654 (/ISO)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
2 P39654 (/IMP) P39654 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 P39655 (/ISO) P39655 (/ISO)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 P39655 (/ISS) P39655 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P39655 (/ISO) P39655 (/ISO)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
2 P39654 (/IMP) P39654 (/IMP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2 P39655 (/ISO) P39655 (/ISO)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
2 O70582 (/ISO) O70582 (/ISO)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
2 P39655 (/ISO) P39655 (/ISO)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
2 D3ZKX9 (/ISS) Q9BYJ1 (/ISS)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
2 P39655 (/ISO) P39655 (/ISO)
Positive regulation of mitochondrial depolarization GO:0051901
Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
2 P39655 (/ISO) P39655 (/ISO)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 O75342 (/IDA) Q7T2A9 (/IDA)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 O70582 (/ISO) O70582 (/ISO)
Positive regulation of mucus secretion GO:0070257
Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
2 O70582 (/ISO) O70582 (/ISO)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
2 P39654 (/ISO) P39654 (/ISO)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
2 P39654 (/ISO) P39654 (/ISO)
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
2 P39655 (/IMP) P39655 (/IMP)
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
2 F1LQ70 (/ISS) P18054 (/ISS)
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
2 P39655 (/ISO) P39655 (/ISO)
Regulation of engulfment of apoptotic cell GO:1901074
Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.
2 P39654 (/IMP) P39654 (/IMP)
Positive regulation of endothelial tube morphogenesis GO:1905956
Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.
2 P39655 (/ISO) P39655 (/ISO)
Lipoxin biosynthetic process GO:2001301
The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.
2 P09917 (/TAS) P18054 (/TAS)
Lipoxin A4 biosynthetic process GO:2001303
The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
2 P39654 (/IMP) P39654 (/IMP)
Lipoxin A4 biosynthetic process GO:2001303
The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
2 P39655 (/ISO) P39655 (/ISO)
Lipoxin B4 biosynthetic process GO:2001306
The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
2 P39655 (/ISO) P39655 (/ISO)
Acute inflammatory response GO:0002526
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
1 P12527 (/IMP)
Acute inflammatory response GO:0002526
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
1 P48999 (/ISO)
Leukotriene production involved in inflammatory response GO:0002540
The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
1 P48999 (/IMP)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 O15296 (/TAS)
Leukotriene metabolic process GO:0006691
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
1 P48999 (/IMP)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 O15296 (/TAS)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
1 P48999 (/IMP)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
1 P16050 (/TAS)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 F1LQ70 (/IEP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 P12527 (/IEP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 O15296 (/IDA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 O15296 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 O35936 (/ISO)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q9XT59 (/ISS)
Negative regulation of muscle cell apoptotic process GO:0010656
Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
1 P18054 (/IMP)
Positive regulation of macrophage derived foam cell differentiation GO:0010744
Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
1 O15296 (/IMP)
Positive regulation of macrophage derived foam cell differentiation GO:0010744
Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
1 O35936 (/ISO)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
1 P16050 (/IDA)
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 F1LQ70 (/IMP)
Leukotriene biosynthetic process GO:0019370
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
1 P48999 (/IMP)
Leukotriene biosynthetic process GO:0019370
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
1 P48999 (/ISO)
Leukotriene biosynthetic process GO:0019370
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
1 P12527 (/TAS)
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
1 P18054 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 O15296 (/TAS)
Prostate gland development GO:0030850
The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
1 O15296 (/NAS)
Regulation of epithelial cell differentiation GO:0030856
Any process that modulates the frequency, rate or extent of epithelial cell differentiation.
1 O15296 (/NAS)
Positive regulation of heterotypic cell-cell adhesion GO:0034116
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
1 Q02759 (/IMP)
Peroxisome proliferator activated receptor signaling pathway GO:0035357
The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.
1 Q9WV07 (/IMP)
Positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360
Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
1 O35936 (/IMP)
Interleukin-18-mediated signaling pathway GO:0035655
A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P09917 (/TAS)
Cellular response to interleukin-13 GO:0035963
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
1 P16050 (/IMP)
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 Q02759 (/TAS)
Superoxide anion generation GO:0042554
The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.
1 P18054 (/NAS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 F1LQ70 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 F1LQ70 (/IMP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
1 F1LQ70 (/IMP)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
1 P09917 (/TAS)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 O75342 (/IDA)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
1 F1LQ70 (/IMP)
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
1 Q9WV07 (/ISO)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
1 Q9WV07 (/IMP)
Positive regulation of keratinocyte differentiation GO:0045618
Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
1 O35936 (/IMP)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 O15296 (/IDA)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 O35936 (/ISO)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 Q9XT59 (/ISS)
Negative regulation of cell volume GO:0045794
Any process that decreases cell volume.
1 Q02759 (/TAS)
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
1 P12527 (/IMP)
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
1 P48999 (/ISO)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 O15296 (/IDA)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 O35936 (/ISO)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 Q9XT59 (/ISS)
Icosanoid biosynthetic process GO:0046456
The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
1 Q02759 (/NAS)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
1 F1LQ70 (/IMP)
Hepoxilin metabolic process GO:0051121
The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
1 P18054 (/TAS)
Hepoxilin biosynthetic process GO:0051122
The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
1 Q9WV07 (/IMP)
Positive regulation of mitochondrial depolarization GO:0051901
Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
1 F1LQ70 (/IMP)
Response to hyperoxia GO:0055093
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
1 P12527 (/IEP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 O75342 (/IMP)
Positive regulation of mucus secretion GO:0070257
Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
1 O75342 (/IMP)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 P16050 (/IMP)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 P16050 (/IDA)
Cellular response to lipid GO:0071396
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
1 F1LQ70 (/IEP)
Positive regulation of chemokine secretion GO:0090197
Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
1 O15296 (/IMP)
Positive regulation of chemokine secretion GO:0090197
Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
1 O35936 (/ISO)
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
1 F1LQ70 (/IMP)
Leukotriene A4 metabolic process GO:1901751
The chemical reactions and pathways involving leukotriene A4.
1 P18054 (/IDA)
Positive regulation of cytochrome-c oxidase activity GO:1904960
Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
1 P12527 (/IMP)
Positive regulation of cytochrome-c oxidase activity GO:1904960
Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
1 P48999 (/ISO)
Positive regulation of endothelial tube morphogenesis GO:1905956
Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.
1 F1LQ70 (/IMP)
Lipoxin A4 biosynthetic process GO:2001303
The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
1 P18054 (/IDA)
Lipoxin B4 biosynthetic process GO:2001306
The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
1 P18054 (/IDA)

There are 49 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 O35936 (/ISS) P12527 (/ISS) P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) P48999 (/ISS) P51399 (/ISS) P51399 (/ISS) Q5RBE8 (/ISS)
(2 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
11 F1LQ70 (/ISS) P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) P39655 (/ISS) P39655 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 F1LQ70 (/IDA) I3L1D5 (/IDA) O15296 (/IDA) P09917 (/IDA) P16050 (/IDA) P18054 (/IDA) P39654 (/IDA) P39654 (/IDA) Q02759 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 F1LQ70 (/IDA) P12527 (/IDA) P18054 (/IDA) P39654 (/IDA) P39654 (/IDA) P39655 (/IDA) P39655 (/IDA) P48999 (/IDA)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
8 P12530 (/ISS) P16469 (/ISS) P27479 (/ISS) P39654 (/ISS) P39654 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P12530 (/ISS) P16050 (/ISS) P16469 (/ISS) P27479 (/ISS) Q02759 (/ISS) Q5RBE8 (/ISS) Q5RBE8 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 O35936 (/ISO) P39654 (/ISO) P39654 (/ISO) P39655 (/ISO) P39655 (/ISO) P48999 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 O15296 (/TAS) O75342 (/TAS) P09917 (/TAS) P16050 (/TAS) P18054 (/TAS) Q9BYJ1 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 O35936 (/ISO) P39654 (/ISO) P39654 (/ISO) P39655 (/ISO) P39655 (/ISO)
Nuclear envelope lumen GO:0005641
The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
4 P12527 (/ISS) P48999 (/ISS) P51399 (/ISS) P51399 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 I3L1D5 (/IDA) O15296 (/IDA) P39654 (/IDA) P39654 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
4 P12527 (/ISS) P48999 (/ISS) P51399 (/ISS) P51399 (/ISS)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
4 F1LQ70 (/ISS) P39655 (/ISS) P39655 (/ISS) Q02759 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P12527 (/IDA) P48999 (/IDA) Q7T2A9 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 A0A087X109 (/IDA) A0A087X109 (/IDA) P09917 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P39655 (/ISO) P39655 (/ISO) P48999 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 O15296 (/IDA) P16050 (/IDA) P18054 (/IDA)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
3 F1LQ70 (/IDA) P12527 (/IDA) P18054 (/IDA)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
3 P39655 (/ISO) P39655 (/ISO) P48999 (/ISO)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 P09917 (/IDA) P12527 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 P09917 (/TAS) P12527 (/TAS)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
2 P39654 (/ISO) P39654 (/ISO)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
2 P39654 (/ISO) P39654 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 O15296 (/HDA) P18054 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P09917 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P09917 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P48999 (/ISO)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
1 P48999 (/ISO)
Nuclear envelope lumen GO:0005641
The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
1 P09917 (/IDA)
Nuclear envelope lumen GO:0005641
The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
1 P48999 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P48999 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 F1LQ70 (/ISS)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
1 P16050 (/IDA)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
1 O15296 (/IDA)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
1 O35936 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O35936 (/ISO)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
1 P09917 (/IDA)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
1 P48999 (/ISO)
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 O15296 (/IDA)
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 O35936 (/ISO)
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 Q8K4F2 (/ISS)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P12527 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P48999 (/ISO)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
1 P16050 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 P09917 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 P48999 (/ISO)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
1 P09917 (/TAS)
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
1 P09917 (/TAS)
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