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CATH Superfamily 2.60.40.790

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 69: Protein lethal(2)essential for life

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
 4 P82147 (/ISM) P82147 (/ISM) P82147 (/ISM) P82147 (/ISM)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
 4 P82147 (/IDA) P82147 (/IDA) P82147 (/IDA) P82147 (/IDA)
Regulation of translational initiation by eIF2 alpha phosphorylation GO:0010998
Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
 4 P82147 (/IMP) P82147 (/IMP) P82147 (/IMP) P82147 (/IMP)
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
 4 P82147 (/IDA) P82147 (/IDA) P82147 (/IDA) P82147 (/IDA)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
 4 P82147 (/IMP) P82147 (/IMP) P82147 (/IMP) P82147 (/IMP)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
 4 P82147 (/ISM) P82147 (/ISM) P82147 (/ISM) P82147 (/ISM)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
 4 P82147 (/IDA) P82147 (/IDA) P82147 (/IDA) P82147 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
 4 P82147 (/IDA) P82147 (/IDA) P82147 (/IDA) P82147 (/IDA)