The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Neutral/alkaline non-lysosomal ceramidase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Hydrolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
N-acylsphingosine amidohydrolase activity GO:0017040
Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.
5 O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
5 O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA)
Sphingosine biosynthetic process GO:0046512
The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
5 O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA)
Ceramide catabolic process GO:0046514
The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.
5 O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA) O06769 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
5 O06769 (/HDA) O06769 (/HDA) O06769 (/HDA) O06769 (/HDA) O06769 (/HDA)
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