The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ephrin a2 ectodomain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Eph receptor tyrosine kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transmembrane-ephrin receptor activity GO:0005005
Combining with a transmembrane ephrin to initiate a change in cell activity.
10 D1YSF9 (/ISS) O96435 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q5BIC7 (/ISS) Q8IMC2 (/ISS) Q8MT37 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
10 D1YSF9 (/IMP) O96435 (/IMP) Q0KIF4 (/IMP) Q59DQ4 (/IMP) Q5BIC7 (/IMP) Q8IMC2 (/IMP) Q8MT37 (/IMP) Q9V4E5 (/IMP) Q9XZL6 (/IMP) Q9Y1J0 (/IMP)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
10 D1YSF9 (/IMP) O96435 (/IMP) Q0KIF4 (/IMP) Q59DQ4 (/IMP) Q5BIC7 (/IMP) Q8IMC2 (/IMP) Q8MT37 (/IMP) Q9V4E5 (/IMP) Q9XZL6 (/IMP) Q9Y1J0 (/IMP)
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
10 D1YSF9 (/IMP) O96435 (/IMP) Q0KIF4 (/IMP) Q59DQ4 (/IMP) Q5BIC7 (/IMP) Q8IMC2 (/IMP) Q8MT37 (/IMP) Q9V4E5 (/IMP) Q9XZL6 (/IMP) Q9Y1J0 (/IMP)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
10 D1YSF9 (/ISS) O96435 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q5BIC7 (/ISS) Q8IMC2 (/ISS) Q8MT37 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
10 D1YSF9 (/ISS) O96435 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q5BIC7 (/ISS) Q8IMC2 (/ISS) Q8MT37 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
10 D1YSF9 (/ISS) O96435 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q5BIC7 (/ISS) Q8IMC2 (/ISS) Q8MT37 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)
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