The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Perfringolysin, domain 4
".
FunFam 1: Thiol-activated cytolysin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
7 | P13128 (/IPI) P13128 (/IPI) P13128 (/IPI) P13128 (/IPI) P13128 (/IPI) P13128 (/IPI) P13128 (/IPI) |
|
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
2 | Q724L1 (/ISS) Q724L1 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
16 |
P0C2E9 (/IMP)
P0C2E9 (/IMP)
P0C2E9 (/IMP)
Q2XU26 (/IMP)
Q2XU26 (/IMP)
Q2XU26 (/IMP)
Q2XU26 (/IMP)
Q2XU26 (/IMP)
Q2XU26 (/IMP)
Q2XU26 (/IMP)
(6 more) |
|
Hemolysis in other organism GO:0044179
The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.
|
3 | P0C2E9 (/IMP) P0C2E9 (/IMP) P0C2E9 (/IMP) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
2 | Q724L1 (/ISS) Q724L1 (/ISS) |
|
Cytolysis GO:0019835
The rupture of cell membranes and the loss of cytoplasm.
|
2 | Q724L1 (/ISS) Q724L1 (/ISS) |
|
Hemolysis by symbiont of host erythrocytes GO:0019836
The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
2 | Q724L1 (/ISS) Q724L1 (/ISS) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.